4rrw

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'''Unreleased structure'''
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==Crystal Structure of Apo Murine Cyclooxygenase-2==
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<StructureSection load='4rrw' size='340' side='right' caption='[[4rrw]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
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The entry 4rrw is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4rrw]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RRW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RRW FirstGlance]. <br>
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Authors: Xu, S., Blobaum, A.L., Banerjee, S., Marnett, L.J.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LUR:{2-[(2-CHLORO-6-FLUOROPHENYL)AMINO]-5-METHYLPHENYL}ACETIC+ACID'>LUR</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rrx|4rrx]], [[4rry|4rry]], [[4rrz|4rrz]], [[4rs0|4rs0]]</td></tr>
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Description: Crystal Structure of Apo Murine Cyclooxygenase-2
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-endoperoxide_synthase Prostaglandin-endoperoxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.1 1.14.99.1] </span></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rrw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rrw RCSB], [http://www.ebi.ac.uk/pdbsum/4rrw PDBsum]</span></td></tr>
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[[Category: Blobaum, A.L]]
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</table>
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[[Category: Xu, S]]
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== Function ==
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[[http://www.uniprot.org/uniprot/PGH2_MOUSE PGH2_MOUSE]] Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.<ref>PMID:12925531</ref> <ref>PMID:20463020</ref> <ref>PMID:20810665</ref> <ref>PMID:21489986</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Prostaglandin-endoperoxide synthase]]
[[Category: Banerjee, S]]
[[Category: Banerjee, S]]
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[[Category: Marnett, L.J]]
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[[Category: Blobaum, A L]]
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[[Category: Marnett, L J]]
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[[Category: Xu, S]]
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[[Category: Glycosylation]]
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[[Category: Membrane]]
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[[Category: Oxidoreductase]]

Revision as of 11:14, 8 April 2015

Crystal Structure of Apo Murine Cyclooxygenase-2

4rrw, resolution 2.57Å

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