4tlv
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==CARDS TOXIN, NICKED== |
| - | + | <StructureSection load='4tlv' size='340' side='right' caption='[[4tlv]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4tlv]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TLV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TLV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4tlw|4tlw]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tlv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tlv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tlv RCSB], [http://www.ebi.ac.uk/pdbsum/4tlv PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: Taylor, A | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/CARDS_MYCPN CARDS_MYCPN]] Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells.<ref>PMID:16617115</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Hart, P J]] | ||
| + | [[Category: Pakhomova, O N]] | ||
| + | [[Category: Taylor, A B]] | ||
| + | [[Category: Adp-ribosyl transferase]] | ||
| + | [[Category: Atypical pneumonia]] | ||
| + | [[Category: Community acquired respiratory distress syndrome]] | ||
| + | [[Category: Mycoplasma pneumoniae]] | ||
| + | [[Category: Toxin]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Virulence]] | ||
Revision as of 11:15, 8 April 2015
CARDS TOXIN, NICKED
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