Sandbox Reserved 978
From Proteopedia
(Difference between revisions)
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| - | {{Telford_CHEM321}}<!-- | + | {{Telford_CHEM321}}<!-- HI DR. T!!!!!!!!! --> |
| - | == | + | ==Thioredoxin Reductase== |
| - | <StructureSection load=' | + | <StructureSection load='2zbw' size='340' side='right' caption='Thioredoxin Reductase=''> |
This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
== Function == | == Function == | ||
| - | + | The protein Thioredoxin Reductase (TrxR) is utilized in the regulation of DNA translation and in apoptosis. A normal stop codon (UGA, UAA, and UAG) stops the translation of the mRNA, but in the presence of TrxR an extra Selenocysteine. This extra protein is what marks the structure for death inside the cell. Enough of these structures in the cell and the entire cell will undergo apoptosis. | |
== Disease == | == Disease == | ||
| - | + | When left unregulated | |
== Relevance == | == Relevance == | ||
Revision as of 13:10, 9 April 2015
| This Sandbox is Reserved from 15-Jan-2015, through 30-May-2015 for use in the course "Biochemistry" taught by Jason Telford at the Maryville University. This reservation includes Sandbox Reserved 977 through Sandbox Reserved 986. |
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Thioredoxin Reductase
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
