2uwp
From Proteopedia
Line 1: | Line 1: | ||
- | [[Image:2uwp.jpg|left|200px]] | + | [[Image:2uwp.jpg|left|200px]] |
- | + | ||
- | '''FACTOR XA INHIBITOR COMPLEX''' | + | {{Structure |
+ | |PDB= 2uwp |SIZE=350|CAPTION= <scene name='initialview01'>2uwp</scene>, resolution 1.75Å | ||
+ | |SITE= <scene name='pdbsite=AC1:Mg+Binding+Site+For+Chain+A'>AC1</scene> | ||
+ | |LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=894:2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE'>894</scene> | ||
+ | |ACTIVITY= [http://en.wikipedia.org/wiki/Coagulation_factor_Xa Coagulation factor Xa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.6 3.4.21.6] | ||
+ | |GENE= | ||
+ | }} | ||
+ | |||
+ | '''FACTOR XA INHIBITOR COMPLEX''' | ||
+ | |||
==Disease== | ==Disease== | ||
Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
- | 2UWP is a [ | + | 2UWP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UWP OCA]. |
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Line 31: | Line 40: | ||
[[Category: blood coagulation]] | [[Category: blood coagulation]] | ||
[[Category: calcium]] | [[Category: calcium]] | ||
- | [[Category: cleavage on pair of basic | + | [[Category: cleavage on pair of basic residue]] |
[[Category: complex]] | [[Category: complex]] | ||
[[Category: egf-like domain]] | [[Category: egf-like domain]] | ||
Line 44: | Line 53: | ||
[[Category: zymogen]] | [[Category: zymogen]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:40:37 2008'' |
Revision as of 16:40, 20 March 2008
| |||||||
, resolution 1.75Å | |||||||
---|---|---|---|---|---|---|---|
Sites: | |||||||
Ligands: | , and | ||||||
Activity: | Coagulation factor Xa, with EC number 3.4.21.6 | ||||||
Coordinates: | save as pdb, mmCIF, xml |
FACTOR XA INHIBITOR COMPLEX
Disease
Known disease associated with this structure: Factor X deficiency OMIM:[227600]
About this Structure
2UWP is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 18:40:37 2008
Categories: Coagulation factor Xa | Homo sapiens | Single protein | Brown, D. | Burns-Kurtis, C L. | Chan, C. | Convery, M A. | Hubbard, J A. | Kelly, H A. | Pateman, A J. | Patikis, A. | Senger, S. | Shah, G P. | Thorpe, J H. | Toomey, J R. | Watson, N S. | Young, R J. | Zhou, P. | 894 | CA | MG | Blood coagulation | Calcium | Cleavage on pair of basic residue | Complex | Egf-like domain | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydroxylation | Polymorphism | Protease | Serine protease | Target hopping | Zymogen