4p14

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'''Unreleased structure'''
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==Crystal structure of Canavalia brasiliensis (ConBr) complexed with adenine==
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<StructureSection load='4p14' size='340' side='right' caption='[[4p14]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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The entry 4p14 is ON HOLD until Apr 12 2016
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4p14]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P14 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P14 FirstGlance]. <br>
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Authors: Delatorre, P., Rocha, B.A.M., Silva-Filho, J.C., Teixeira, C.S., Cavada, B.S., Nascimento, K.S., Neto, I.L.B., Nobrega, R.B., Nagano, C.S., Sampaio, A.H., Holanda, E., Leal, R.B.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p14 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p14 RCSB], [http://www.ebi.ac.uk/pdbsum/4p14 PDBsum]</span></td></tr>
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Description: Crystal structure of Canavalia brasiliensis (ConBr) complexed with adenine
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</table>
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[[Category: Unreleased Structures]]
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== Function ==
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[[Category: Nascimento, K.S]]
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[[http://www.uniprot.org/uniprot/CONA_CANBR CONA_CANBR]] Glucose/D-mannose specific lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>
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[[Category: Teixeira, C.S]]
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== References ==
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[[Category: Silva-Filho, J.C]]
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<references/>
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[[Category: Holanda, E]]
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__TOC__
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[[Category: Neto, I.L.B]]
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</StructureSection>
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[[Category: Nobrega, R.B]]
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[[Category: Canavalia brasiliensis]]
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[[Category: Cavada, B.S]]
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[[Category: Cavada, B S]]
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[[Category: Rocha, B.A.M]]
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[[Category: Leal, R.B]]
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[[Category: Delatorre, P]]
[[Category: Delatorre, P]]
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[[Category: Sampaio, A.H]]
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[[Category: Holanda, E]]
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[[Category: Nagano, C.S]]
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[[Category: Leal, R B]]
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[[Category: Nagano, C S]]
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[[Category: Nascimento, K S]]
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[[Category: Neto, I L.B]]
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[[Category: Nobrega, R B]]
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[[Category: Rocha, B A.M]]
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[[Category: Sampaio, A H]]
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[[Category: Silva-Filho, J C]]
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[[Category: Teixeira, C S]]
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[[Category: Adenine]]
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[[Category: Lectin]]
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[[Category: Sugar binding protein]]

Revision as of 12:57, 15 April 2015

Crystal structure of Canavalia brasiliensis (ConBr) complexed with adenine

4p14, resolution 2.00Å

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