4p55
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of DNA binding domain of K11 from KSHV== |
| - | + | <StructureSection load='4p55' size='340' side='right' caption='[[4p55]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4p55]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P55 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P55 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p55 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p55 RCSB], [http://www.ebi.ac.uk/pdbsum/4p55 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[Category: | + | == Function == |
| - | [[Category: Gao, Z | + | [[http://www.uniprot.org/uniprot/VIRF2_HHV8P VIRF2_HHV8P]] Plays a role in the inhibition of host immune response. Acts by interacting with host EIF2AK2/PKR and inhibiting its activation. In turn, EIF2AK2/PKR substrates including EIF2S1 or histone H2A are not phosphorylated.<ref>PMID:11160738</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Dong, Y H]] | ||
| + | [[Category: Gao, Z Q]] | ||
| + | [[Category: Hu, H D]] | ||
[[Category: Lan, K]] | [[Category: Lan, K]] | ||
| - | [[Category: | + | [[Category: Dna binding protein]] |
| + | [[Category: Interferon regulatory factor]] | ||
Revision as of 12:58, 15 April 2015
Crystal structure of DNA binding domain of K11 from KSHV
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