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Heat Shock Proteins
From Proteopedia
| Line 101: | Line 101: | ||
**[[2v7y]] – Hsp70 NBD+sub – ''Geobacillus kaustophilus'' | **[[2v7y]] – Hsp70 NBD+sub – ''Geobacillus kaustophilus'' | ||
| - | *DnaK (Hsp70 from E. coli) | + | *DnaK (Hsp70 from ''E. coli'') |
**[[2kho]] – EcDnaK – NMR<br /> | **[[2kho]] – EcDnaK – NMR<br /> | ||
| Line 116: | Line 116: | ||
**[[4r5g]] - EcDnaK CT + inhibitor<br /> | **[[4r5g]] - EcDnaK CT + inhibitor<br /> | ||
**[[4rtf]] DnaK + ATP – ''Mycobacterium tuberculosis''<br /> | **[[4rtf]] DnaK + ATP – ''Mycobacterium tuberculosis''<br /> | ||
| - | |||
*Hsp83 | *Hsp83 | ||
| Line 217: | Line 216: | ||
**[[1r6b]], [[1ksf]] – EcClpA (mutant) <br /> | **[[1r6b]], [[1ksf]] – EcClpA (mutant) <br /> | ||
**[[4ciu]] - EcClpB (mutant)<br /> | **[[4ciu]] - EcClpB (mutant)<br /> | ||
| - | **[[4d2u]], [[4d2x]] - EcClpB – Cryo EM<br /> | + | **[[4d2u]], [[4d2x]], [[4d2q]] - EcClpB – Cryo EM<br /> |
**[[1khy]] – EcClpB NTD <br /> | **[[1khy]] – EcClpB NTD <br /> | ||
| - | **[[1jbk]] – EcClpB | + | **[[1jbk]] – EcClpB nucleotide binding domain 1<br /> |
**[[1k6k]] - EcClpA NTD<br /> | **[[1k6k]] - EcClpA NTD<br /> | ||
**[[4iod]], [[4irf]] - PfClpB <br /> | **[[4iod]], [[4irf]] - PfClpB <br /> | ||
| + | **[[1qvr]] - TtClpB <br /> | ||
| + | **[[4fct]] - TtClpB CT<br /> | ||
| + | **[[4lj4]] - TtClpB nucleotide binding domain 2<br /> | ||
| + | **[[4hse]] - TtClpB nucleotide binding domain 1 + ADP<br /> | ||
| + | **[[4lj5]] - TtClpB nucleotide binding domain 2 + ADP<br /> | ||
| + | **[[4lj6]] - TtClpB nucleotide binding domain 2 + AMPPCP<br /> | ||
| + | **[[4lj9]], [[4lja]] - TtClpB nucleotide binding domain 2 (mutant) + AMPPCP<br /> | ||
| + | **[[4lj8]] - TtClpB nucleotide binding domain 2 (mutant) + ADP <br /> | ||
| + | **[[4lj7]] - TtClpB nucleotide binding domain 2 (mutant) + ADP derivative<br /> | ||
| + | **[[4fcv]], [[4fcw]], [[4fd2]] - TtClpB CT (mutant)<br /> | ||
| + | **[[3zri]] - VcClpB NTD – ''Vibrio cholerae''<br /> | ||
| + | **[[3zrj]] - VcClpB NTD + peptide<br /> | ||
| + | |||
* Hsp110 in mammals is named Sse1, Sse2 in yeast | * Hsp110 in mammals is named Sse1, Sse2 in yeast | ||
Revision as of 09:59, 16 April 2015
Heat Shock Proteins (Hsp). The Hsp are proteins which are expressed when cells are exposed to stresses like heat. Hsp60, Hsp70, Hsp90 etc. are named according to their molecular weights. Their function is to provide protection from stress. Hsp contains a nucleotide-binding domain (NBD), a substrate-binding domain (sub) and C-terminal lid domain (lid). In E. coli there are additional Hsp – HslV (19kD), HslJ and HslU (50kD). The heat-inducible Hsp is called heat shock cognate protein (Hsc). Hsp70 from E. coli is called DnaK.
See also
- Chaperones
- Hsp100
- Hsp40
- Molecular Playground/DnaK for Hsp70 in E. coli
- Molecular Playground/sHSP for small Hsp
3D Structures of Heat Shock Proteins
Updated on 16-April-2015
