Hepatocyte growth factor receptor
From Proteopedia
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**[[3dkc]], [[3dkf]], [[3dkg]], [[1r1w]] – hHGFR tyrosine kinase domain (mutant) <br /> | **[[3dkc]], [[3dkf]], [[3dkg]], [[1r1w]] – hHGFR tyrosine kinase domain (mutant) <br /> | ||
- | *HGFR | + | *HGFR complex |
**[[1r0p]] – hHGFR tyrosine kinase domain (mutant) + K-252A <br /> | **[[1r0p]] – hHGFR tyrosine kinase domain (mutant) + K-252A <br /> | ||
**[[2uzx]], [[2uzy]] – hHGFR SEMA, ψ, Ig1, Met741 domains + internalin B <br /> | **[[2uzx]], [[2uzy]] – hHGFR SEMA, ψ, Ig1, Met741 domains + internalin B <br /> | ||
- | **[[2rfn]], [[2rfs]], [[3ccn]], [[3cd8]], [[3f66]], [[2wd1]], [[2wgj]], [[3l8v]], [[3lq8]], [[2wkm]], [[3q6w]], [[3rhk]], [[3qti]], [[3zxz]], [[3zze]], [[3r7o]], [[3u6h]], [[3u6i]], [[4deg]], [[4deh]], [[4dei]], [[4aoi]], [[4ap7]], [[4gg5]], [[4gg7]], [[4eev]] – hHGFR tyrosine kinase domain + inhibitor <br /> | + | **[[2rfn]], [[2rfs]], [[3ccn]], [[3cd8]], [[3f66]], [[2wd1]], [[2wgj]], [[3l8v]], [[3lq8]], [[2wkm]], [[3q6w]], [[3rhk]], [[3qti]], [[3zxz]], [[3zze]], [[3r7o]], [[3u6h]], [[3u6i]], [[4deg]], [[4deh]], [[4dei]], [[4aoi]], [[4ap7]], [[4gg5]], [[4gg7]], [[4eev]], [[4knb]], [[4mxc]], [[4r1v]], [[4r1y]], [[4xmo]], [[4xyf]] – hHGFR tyrosine kinase domain + inhibitor <br /> |
**[[3c1x]], [[3cth]], [[3ctj]], [[3ce3]], [[3efj]], [[3efk]], [[3f82]], [[3i5n]], [[3a4p]] – hHGFR tyrosine kinase domain (mutant) + inhibitor <br /> | **[[3c1x]], [[3cth]], [[3ctj]], [[3ce3]], [[3efj]], [[3efk]], [[3f82]], [[3i5n]], [[3a4p]] – hHGFR tyrosine kinase domain (mutant) + inhibitor <br /> | ||
- | **[[1shy]] – hHGFR SEMA and ψ domain + hHGF β chain – | + | **[[1shy]] – hHGFR SEMA and ψ domain + hHGF β chain <br /> |
+ | **[[4o3t]], [[4o3u]] – hHGFR SEMA and ψ domain (mutant) + hHGF α chain (mutant) + zymogen activator peptide<br /> | ||
**[[3vw8]], [[3zbx]], [[3zc5]], [[3zcl]], [[4iwd]] - hHGFR tyrosine kinase domain + inhibitor<br /> | **[[3vw8]], [[3zbx]], [[3zc5]], [[3zcl]], [[4iwd]] - hHGFR tyrosine kinase domain + inhibitor<br /> | ||
}} | }} |
Revision as of 10:20, 20 April 2015
|
3D Structures of hepatocyte growth factor receptor
Updated on 20-April-2015
References
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100
- ↑ http://en.wikipedia.org/wiki/C-Met
- ↑ Maina F, Casagranda F, Audero E, Simeone A, Comoglio PM, Klein R, Ponzetto C. Uncoupling of Grb2 from the Met receptor in vivo reveals complex roles in muscle development. Cell. 1996 Nov 1;87(3):531-42. PMID:8898205
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100
- ↑ Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100