Importin

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Line 19: Line 19:
*IPO-α
*IPO-α
-
**[[1ial]] – mIPO residues 44-496 – mouse<br />
+
**[[1ial]] – mIPO NLS-binding domain – mouse<br />
**[[1bk5]] – yIPO NLS-binding domain - yeast<br />
**[[1bk5]] – yIPO NLS-binding domain - yeast<br />
 +
**[[4tnm]] – IPO armadillo repeat domain – ''Arabidopsis thaliana''<br />
*''IPO-α complex with NLS peptide''
*''IPO-α complex with NLS peptide''
Line 27: Line 28:
**[[1ejy]] – mIPO NLS-binding domain + nucleoplasmin <br />
**[[1ejy]] – mIPO NLS-binding domain + nucleoplasmin <br />
**[[2ynr]] – mIPO NLS-binding domain + B54NLS <br />
**[[2ynr]] – mIPO NLS-binding domain + B54NLS <br />
 +
**[[2yns]] – rIPO NLS-binding domain + B54NLS - rice<br />
**[[1bk6]] – yIPO NLS-binding domain + SV40 large T antigen<br />
**[[1bk6]] – yIPO NLS-binding domain + SV40 large T antigen<br />
**[[1ee4]] – yIPO NLS-binding domain (mutant) + c-Myc<br />
**[[1ee4]] – yIPO NLS-binding domain (mutant) + c-Myc<br />
Line 35: Line 37:
**[[1wa5]] – yIPO NLS-binding domain + GTPase Ran + IPO-α re-exporter<br />
**[[1wa5]] – yIPO NLS-binding domain + GTPase Ran + IPO-α re-exporter<br />
 +
 +
*IPO-α 1
 +
 +
**[[3wpt]] – hIPO NLS-binding domain - human<br />
 +
**[[4b8j]] – rIPO <br />
*''IPO-α 1 complex with NLS peptide''
*''IPO-α 1 complex with NLS peptide''
Line 40: Line 47:
**[[4mz5]], [[4mz6]] – mIPO NLS-binding domain + dUTPase<br />
**[[4mz5]], [[4mz6]] – mIPO NLS-binding domain + dUTPase<br />
**[[4oih]] – mIPO NLS-binding domain + guanine nucleotide exchange factor SRM1<br />
**[[4oih]] – mIPO NLS-binding domain + guanine nucleotide exchange factor SRM1<br />
 +
**[[4b18]] – hIPO NLS-binding domain + telomerase reverse transcriptase<br />
 +
**[[4wv6]] – hIPO NLS-binding domain + TFIID<br />
 +
**[[4b8o]] – rIPO NLS-binding domain + SV40<br />
 +
**[[4b8p]] – rIPO NLS-binding domain + A89<br />
 +
**[[4bpl]] – rIPO NLS-binding domain + nucleoplasmin<br />
 +
**[[4bqk]] – rIPO NLS-binding domain + VirD2<br />
*''IPO-α 1 complex with protein''
*''IPO-α 1 complex with protein''
Line 46: Line 59:
**[[3tj3]] – hIPO NLS-binding domain + Nup50 N terminal<br />
**[[3tj3]] – hIPO NLS-binding domain + Nup50 N terminal<br />
**[[2jdq]] – hIPO NLS-binding domain + telomerase reverse transcriptase peptide<br />
**[[2jdq]] – hIPO NLS-binding domain + telomerase reverse transcriptase peptide<br />
 +
**[[4uaf]] – mIPO NLS-binding domain + influenza RNA polymerase<br />
*IPO-α 2
*IPO-α 2
Line 51: Line 65:
**[[3tpo]] – mIPO<br />
**[[3tpo]] – mIPO<br />
**[[1iq1]] – mIPO NLS-binding + autoinhibitory peptide domains<br />
**[[1iq1]] – mIPO NLS-binding + autoinhibitory peptide domains<br />
-
**[[4e4v]] – hIPO NLS-binding domain (mutant) - human <br />
+
**[[4e4v]] – hIPO NLS-binding domain (mutant) <br />
*''IPO-α 2 complex with NLS peptide''
*''IPO-α 2 complex with NLS peptide''
Line 80: Line 94:
**[[3fex]], [[3fey]] – mIPO NLS-binding domain + nuclear CAP-binding protein<br />
**[[3fex]], [[3fey]] – mIPO NLS-binding domain + nuclear CAP-binding protein<br />
 +
 +
*IPO-α 3
 +
 +
**[[4uae]] – hIPO NLS-binding domain + influenza RNA polymerase<br />
 +
 +
*IPO-α 6
 +
 +
**[[4u2x]] – hIPO C terminal + ebola VP24<br />
 +
 +
*IPO-α 7
 +
 +
**[[4uad]] – hIPO NLS-binding domain + influenza RNA polymerase<br />
*IPO-β 1
*IPO-β 1
Line 109: Line 135:
**[[4fdd]], [[4jlq]], [[4oo6]] – hIPO + RNA binding protein peptide<br />
**[[4fdd]], [[4jlq]], [[4oo6]] – hIPO + RNA binding protein peptide<br />
**[[4fq3]] – hIPO + FUS peptide<br />
**[[4fq3]] – hIPO + FUS peptide<br />
 +
 +
*IPO-β 3 (Karyopherin)
 +
 +
**[[3w3t]] – yIPO <br />
 +
**[[3w3u]], [[3w3v]] – yIPO (mutant)<br />
 +
**[[3w3w]] – yIPO + STE12P<br />
 +
**[[3w3x]] – yIPO + PHO4<br />
 +
**[[3w3y]] – yIPO + Nup53P<br />
 +
**[[3w3z]] – yIPO + RANGTP<br />
 +
 +
*IPO-12 (Transportin-3)
 +
 +
**[[4c0p]] – hIPO <br />
 +
**[[4c0o]] – hIPO + serine/arginine-rich splicing factor<br />
 +
**[[4c0q]], [[4ol0]] – hIPO + GTPase Ran<br />
*IPO-13
*IPO-13

Revision as of 10:02, 22 April 2015

Structure of yeast importin α NLS-binding domain (grey) complex with nucleoplasmin peptide (green) (PDB code 1ee5).

Drag the structure with the mouse to rotate

3D structures of importin

Updated on 22-April-2015

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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