Inosine monophosphate dehydrogenase

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Line 25: Line 25:
**[[3ffs]] – CpIMPDH – ''Cryptosporidium parvum''<br />
**[[3ffs]] – CpIMPDH – ''Cryptosporidium parvum''<br />
**[[3r2g]] – IMPDH – ''Legionella pneumophila'' <br />
**[[3r2g]] – IMPDH – ''Legionella pneumophila'' <br />
-
**[[3tsb]], [[4mjm]] – BaIMPDH (mutant) – ''Bacillus anthracis'' <br />
+
**[[3tsb]], [[4mjm]], [[4myx]] – BaIMPDH (mutant) – ''Bacillus anthracis'' <br />
**[[4fez]] – VcIMPDH – ''Vibrio cholerae'' <br />
**[[4fez]] – VcIMPDH – ''Vibrio cholerae'' <br />
**[[4avf]], [[3zfh]] – PaIMPDH – ''Pseudomonas aeruginosa'' <br />
**[[4avf]], [[3zfh]] – PaIMPDH – ''Pseudomonas aeruginosa'' <br />
Line 38: Line 38:
**[[3usb]] – BaIMPDH + inosinic acid <br />
**[[3usb]] – BaIMPDH + inosinic acid <br />
**[[4ix2]] – VcIMPDH + inosinic acid <br />
**[[4ix2]] – VcIMPDH + inosinic acid <br />
 +
**[[4qq3]] – VcIMPDH (mutant) + XMP <br />
**[[4dqw]] – PaIMPDH + ATP <br />
**[[4dqw]] – PaIMPDH + ATP <br />
 +
**[[1jcn]] – hMPDH 1 + IMP derivative - human<br />
 +
**[[1jr1]] – hMPDH 2 + mycophenolic acid <br />
 +
**[[4r7j]] – CjIMPDH catalytic domain (mutant) + inosinic acid – ''Campylobacter jejuni''<br />
*IMPDH ternary complex
*IMPDH ternary complex
Line 47: Line 51:
**[[1mei]] – TfIMPDH + mycophenolic acid + xanthosine monophosphate <br />
**[[1mei]] – TfIMPDH + mycophenolic acid + xanthosine monophosphate <br />
**[[1mew]] – TfIMPDH + NAD + xanthosine monophosphate <br />
**[[1mew]] – TfIMPDH + NAD + xanthosine monophosphate <br />
-
**[[3khj]] – CpIMPDH + inhibitor + inosinic acid <br />
 
**[[4fo4]], [[4fxs]] – VcIMPDH + mycophenolic acid + inosinic acid <br />
**[[4fo4]], [[4fxs]] – VcIMPDH + mycophenolic acid + inosinic acid <br />
**[[4hlv]] – VcIMPDH + NAD + inosinic acid <br />
**[[4hlv]] – VcIMPDH + NAD + inosinic acid <br />
-
**[[4ixh]] – CpIMPDH catalytic domain + benzoxazole inhibitor + inosinic acid <br />
+
**[[4qne]] – VcIMPDH (mutant) + NAD + IMP <br />
-
**[[4my8]] – BaIMPDH catalytic domain (mutant) + benzoxazole inhibitor + inosinic acid <br />
+
**[[4x3z]] – VcIMPDH (mutant) + NAD + XMP <br />
 +
**[[4ixh]], [[3khj]], [[4qj1]] – CpIMPDH catalytic domain + inhibitor + inosinic acid <br />
 +
**[[4rv8]] - CpIMPDH catalytic domain (mutant) + inhibitor + inosinic acid <br />
**[[4my1]], [[4mya]], [[4mxs]], [[4my9]] – BaIMPDH catalytic domain (mutant) + inhibitor + inosinic acid <br />
**[[4my1]], [[4mya]], [[4mxs]], [[4my9]] – BaIMPDH catalytic domain (mutant) + inhibitor + inosinic acid <br />
-
**[[4mz1]] – IMPDH catalytic domain (mutant) + inhibitor + inosinic acid – ''Campylobacter jejuni''<br />
+
**[[4mz1]], [[4mz8]] – CjIMPDH catalytic domain (mutant) + inhibitor + inosinic acid <br />
 +
**[[4q32]], [[4q33]] – MPDH + IMP + inhibitor – ''Clostridium perfringens'' <br />
**[[4af0]] – IMPDH + mycophenolic acid + inosinic acid – ''Cryptococcus neoformans''<br />
**[[4af0]] – IMPDH + mycophenolic acid + inosinic acid – ''Cryptococcus neoformans''<br />
 +
**[[1b3o]] – hMPDH 2 + selenazole inhibitor + IMP derivative <br />
 +
**[[1nfb]] – hMPDH 2 + NAD + IMP derivative <br />
 +
**[[1nf7]] – hMPDH 2 + mycophenolic adenine dinucleotide + ribavirin monophosphate <br />
 +
}}
}}
== References ==
== References ==

Revision as of 11:13, 22 April 2015

Structure of IMPDH complex with inosinic acid, K+ (purple) and the inhibitor mycophenolic acid (PDB code 4fo4).

Drag the structure with the mouse to rotate

3D structures of inosine monophosphate dehydrogenase

Updated on 22-April-2015

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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