4z02

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'''Unreleased structure'''
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==Crystal structure of BRD1 in complex with Isoquinoline-3-carboxylic acid==
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<StructureSection load='4z02' size='340' side='right' caption='[[4z02]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
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The entry 4z02 is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4z02]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z02 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z02 FirstGlance]. <br>
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Authors: DONG, A., IQBAL, A., WALKER, J.R., Bountra, C., Arrowsmith, C.H., Edwards, A.M., BROWN, P.J., Structural Genomics Consortium (SGC)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4K8:ISOQUINOLINE-3-CARBOXYLIC+ACID'>4K8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z02 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z02 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4z02 RCSB], [http://www.ebi.ac.uk/pdbsum/4z02 PDBsum]</span></td></tr>
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Description: Crystal structure of BRD1 in complex with Isoquinoline-3-carboxylic acid
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</table>
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[[Category: Unreleased Structures]]
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== Function ==
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[[Category: Dong, A]]
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[[http://www.uniprot.org/uniprot/BRD1_HUMAN BRD1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.<ref>PMID:16387653</ref> <ref>PMID:21880731</ref>
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[[Category: Walker, J.R]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Arrowsmith, C H]]
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[[Category: BROWN, P J]]
[[Category: Bountra, C]]
[[Category: Bountra, C]]
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[[Category: Arrowsmith, C.H]]
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[[Category: DONG, A]]
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[[Category: Iqbal, A]]
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[[Category: Edwards, A M]]
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[[Category: Brown, P.J]]
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[[Category: IQBAL, A]]
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[[Category: Edwards, A.M]]
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[[Category: Structural genomic]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: WALKER, J R]]
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[[Category: Brd1]]
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[[Category: Brpf2 fragment]]
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[[Category: Histone-binding protein]]
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[[Category: Sgc]]

Revision as of 12:56, 22 April 2015

Crystal structure of BRD1 in complex with Isoquinoline-3-carboxylic acid

4z02, resolution 1.87Å

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