1q44

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<StructureSection load='1q44' size='340' side='right' caption='[[1q44]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='1q44' size='340' side='right' caption='[[1q44]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1q44]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q44 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Q44 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1q44]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q44 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Q44 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1q45|1q45]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1q45|1q45]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">At2g03760 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">At2g03760 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1q44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q44 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1q44 RCSB], [http://www.ebi.ac.uk/pdbsum/1q44 PDBsum], [http://www.topsan.org/Proteins/CESG/1q44 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1q44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q44 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1q44 RCSB], [http://www.ebi.ac.uk/pdbsum/1q44 PDBsum], [http://www.topsan.org/Proteins/CESG/1q44 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FSTL_ARATH FSTL_ARATH]] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the stereospecific sulfate conjugation of 24-epibrassinosteroids. Preferred substrates are 24-epicathasterone and 6-deoxo-24-epicathasterone. Low activity with 22-deoxy-24-epiteasterone. No activity with 24-epimers catasterone and brassinolide. Sulfonates salicylic acid. May be involved in detoxification. Enhances plant response to pathogen infection and contributes to long distance signaling in systemic acquired resistance (SAR).<ref>PMID:17039368</ref> <ref>PMID:20374532</ref>
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[[http://www.uniprot.org/uniprot/SOT12_ARATH SOT12_ARATH]] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the stereospecific sulfate conjugation of 24-epibrassinosteroids. Preferred substrates are 24-epicathasterone and 6-deoxo-24-epicathasterone. Low activity with 22-deoxy-24-epiteasterone. No activity with 24-epimers catasterone and brassinolide. Sulfonates salicylic acid. May be involved in detoxification. Enhances plant response to pathogen infection and contributes to long distance signaling in systemic acquired resistance (SAR).<ref>PMID:17039368</ref> <ref>PMID:20374532</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arabidopsis thaliana]]
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[[Category: Arath]]
[[Category: Bingman, C A]]
[[Category: Bingman, C A]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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[[Category: Smith, D W]]
[[Category: Smith, D W]]
[[Category: Apo]]
[[Category: Apo]]
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[[Category: Arabidopsis thaliana]]
[[Category: Cesg]]
[[Category: Cesg]]
[[Category: PSI, Protein structure initiative]]
[[Category: PSI, Protein structure initiative]]
[[Category: Steroid sulfotransferase]]
[[Category: Steroid sulfotransferase]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 05:30, 30 April 2015

Crystal Structure of an Arabidopsis Thaliana Putative Steroid Sulfotransferase

1q44, resolution 1.90Å

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