Pantothenate synthetase
From Proteopedia
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*Pantothenate synthetase binary complex with inhibitor | *Pantothenate synthetase binary complex with inhibitor | ||
| - | **[[3cow]], [[3coy]], [[3coz]], [[3imc]], [[3ime]], [[3img]], [[3iub]], [[3iue]], [[3ivc]], [[3ivg]], [[3ivx]], [[3isj]], [[3le8]], [[4ddh]], [[4ddk]], [[4ddm]], [[4de5]], [[4ef6]], [[4efk]], [[4fzj]], [[4g5f]] - MtPS (mutant) + inhibitor | + | **[[3cow]], [[3coy]], [[3coz]], [[3imc]], [[3ime]], [[3img]], [[3iub]], [[3iue]], [[3ivc]], [[3ivg]], [[3ivx]], [[3isj]], [[3le8]], [[4ddh]], [[4ddk]], [[4ddm]], [[4de5]], [[4ef6]], [[4efk]], [[4fzj]], [[4g5f]], [[4mq6]], [[4mue]], [[4muf]], [[4mug]], [[4muh]], [[4mui]], [[4muj]], [[4muk]], [[4mul]], [[4mun]] - MtPS (mutant) + inhibitor |
*Pantothenate synthetase ternary complex | *Pantothenate synthetase ternary complex | ||
Revision as of 10:28, 7 May 2015
Pantothenate synthetase (PS) catalyzes the ATP-dependent condensation of pantoate and β-alanine to form pantothenate. Pantothenate (vitamin B5) biosynthesis is essential for the virulence of Mycobacterium tuberculosis thus its blockage can be used as a potential drug target.
3D structures of pantothenate synthetase
Updated on 07-May-2015
