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Plasminogen activator
From Proteopedia
(Difference between revisions)
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**[[1kdu]] - hTPA kringle domain – NMR<br /> | **[[1kdu]] - hTPA kringle domain – NMR<br /> | ||
**[[1tpm]], [[1tpn]] - hTPA fibrin-binding domain – NMR | **[[1tpm]], [[1tpn]] - hTPA fibrin-binding domain – NMR | ||
| + | |||
| + | *Coagulase/fibrinolysin | ||
| + | |||
| + | **[[2x55]], [[2x56]] - YpTPA – ''Yersinia pestis''<br /> | ||
| + | **[[2x4m]] - YpTPA (mutant)<br /> | ||
| + | **[[4dcb]] - YpTPA (mutant) + plasminogen peptide<br /> | ||
| + | |||
*Urokinase-type plasminogen activator see [[Urokinase]] | *Urokinase-type plasminogen activator see [[Urokinase]] | ||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 11:12, 13 May 2015
Plasminogen activator (PLA) is a serine protease which converts plasminogen to plasmin. It includes Tissue PLA (TPA) which is involved in breakdown of blood clots and urokinase-type PLA Urokinase. TPA structure contains heavy and light chains (HC, LC). PLA is inhibited by PLA inhibitor 1 and 2.
3D structures of plasminogen activator
Updated on 13-May-2015
