4nxq
From Proteopedia
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| - | ''' | + | ==Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) in Complex With Caspr4 Peptide== |
| - | + | <StructureSection load='4nxq' size='340' side='right' caption='[[4nxq]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4nxq]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NXQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NXQ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3kzd|3kzd]], [[3kze|3kze]], [[4gvd|4gvd]], [[4gvc|4gvc]], [[4nxr|4nxr]], [[4nxp|4nxp]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nxq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nxq RCSB], [http://www.ebi.ac.uk/pdbsum/4nxq PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/TIAM1_HUMAN TIAM1_HUMAN]] Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. [[http://www.uniprot.org/uniprot/CNTP4_HUMAN CNTP4_HUMAN]] Presynaptic protein involved in both dopaminergic synaptic transmission and GABAergic system, thereby participating in the structural maturation of inhibitory interneuron synapses. Involved in the dopaminergic synaptic transmission by attenuating dopamine release through a presynaptic mechanism. Also participates in the GABAergic system (By similarity). |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Fuentes, E J]] | ||
| + | [[Category: Hengel, S R]] | ||
[[Category: Liu, X]] | [[Category: Liu, X]] | ||
| - | [[Category: | + | [[Category: Shepherd, T R]] |
| - | [[Category: | + | [[Category: Speckhard, D C]] |
| - | [[Category: | + | [[Category: Beta barrel fold protein]] |
| + | [[Category: Pdz domain]] | ||
| + | [[Category: Peptide binding]] | ||
| + | [[Category: Protein-peptide complex]] | ||
| + | [[Category: Scaffold signaling protein for cell adhesion and cell junction]] | ||
| + | [[Category: Signaling domain]] | ||
| + | [[Category: Signaling protein-peptide complex]] | ||
| + | [[Category: Specificity mutant]] | ||
Revision as of 12:21, 13 May 2015
Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) in Complex With Caspr4 Peptide
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Categories: Fuentes, E J | Hengel, S R | Liu, X | Shepherd, T R | Speckhard, D C | Beta barrel fold protein | Pdz domain | Peptide binding | Protein-peptide complex | Scaffold signaling protein for cell adhesion and cell junction | Signaling domain | Signaling protein-peptide complex | Specificity mutant
