4xk4

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'''Unreleased structure'''
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==E. coli transcriptional regulator RUTR with dihydrouracil==
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<StructureSection load='4xk4' size='340' side='right' caption='[[4xk4]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
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The entry 4xk4 is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4xk4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XK4 FirstGlance]. <br>
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Authors: Shumilin, I.A., Cooper, D.R., Shabalin, I.G., Grabowski, M., Almo, S.C., Minor, W., New York Structural Genomics Research Consortium (NYSGRC)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DUC:DIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE'>DUC</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jyk|4jyk]]</td></tr>
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Description: E. coli transcriptional regulator RUTR with dihydrouracil
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xk4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xk4 RCSB], [http://www.ebi.ac.uk/pdbsum/4xk4 PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Almo, S.C]]
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== Function ==
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[[Category: Shumilin, I.A]]
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[[http://www.uniprot.org/uniprot/RUTR_ECOLI RUTR_ECOLI]] Master transcription regulator which represses the degradation of pyrimidines (rutABCDEFG) and purines (gcl operon) for maintenance of metabolic balance between pyrimidines and purines. It also regulates the synthesis of pyrimidine nucleotides and arginine from glutamine (carAB) and the supply of glutamate (gadABWX).<ref>PMID:16540542</ref> <ref>PMID:17919280</ref>
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[[Category: Minor, W]]
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== References ==
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[[Category: Shabalin, I.G]]
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<references/>
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[[Category: New York Structural Genomics Research Consortium (Nysgrc)]]
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__TOC__
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</StructureSection>
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[[Category: Almo, S C]]
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[[Category: Cooper, D R]]
[[Category: Grabowski, M]]
[[Category: Grabowski, M]]
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[[Category: Cooper, D.R]]
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[[Category: Minor, W]]
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[[Category: Structural genomic]]
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[[Category: Shabalin, I G]]
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[[Category: Shumilin, I A]]
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[[Category: Helix-turn-helix]]
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[[Category: Nysgrc]]
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[[Category: Psi-biology]]
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[[Category: Transcription regulator]]
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[[Category: Transcriptional regulator]]

Revision as of 12:25, 13 May 2015

E. coli transcriptional regulator RUTR with dihydrouracil

4xk4, resolution 2.27Å

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