This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4orb
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Crytal structure of mouse calcineurin== |
| - | + | <StructureSection load='4orb' size='340' side='right' caption='[[4orb]], [[Resolution|resolution]] 3.11Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4orb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ORB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ORB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4or9|4or9]], [[4ora|4ora]], [[4orc|4orc]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoprotein_phosphatase Phosphoprotein phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.16 3.1.3.16] </span></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4orb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4orb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4orb RCSB], [http://www.ebi.ac.uk/pdbsum/4orb PDBsum]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Li, S | + | [[http://www.uniprot.org/uniprot/PP2BA_MOUSE PP2BA_MOUSE]] Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L and HSPB1 (By similarity). Dephosphorylates SSH1.<ref>PMID:1328240</ref> [[http://www.uniprot.org/uniprot/CANB1_MOUSE CANB1_MOUSE]] Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Phosphoprotein phosphatase]] | ||
| + | [[Category: Li, S J]] | ||
[[Category: Ma, L]] | [[Category: Ma, L]] | ||
[[Category: Wang, J]] | [[Category: Wang, J]] | ||
| + | [[Category: Wang, Z X]] | ||
| + | [[Category: Wu, J W]] | ||
| + | [[Category: Calmodulin-binding]] | ||
| + | [[Category: Hydrolase-metal binding protein complex]] | ||
Revision as of 12:15, 20 May 2015
Crytal structure of mouse calcineurin
| |||||||||||
