Retinoblastoma-binding protein
From Proteopedia
(Difference between revisions)
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to a Jmol applet. Check out the other buttons as well! | to a Jmol applet. Check out the other buttons as well! | ||
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| - | '''Retinoblastoma-binding protein''' (RBBP) are nuclear proteins implicated in the regulation of transcription and differentiation by the retinoblastoma tumor suppressor protein.<br /> | + | '''Retinoblastoma-binding protein''' (RBBP) or '''histone-binding protein''' are nuclear proteins implicated in the regulation of transcription and differentiation by the retinoblastoma tumor suppressor protein.<br /> |
* '''RBBP1''' regulates transcriptional activity.<br /> | * '''RBBP1''' regulates transcriptional activity.<br /> | ||
* '''RBBP2''' demethylates histone H3 at lysine 4.<br /> | * '''RBBP2''' demethylates histone H3 at lysine 4.<br /> | ||
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**[[3gfc]] – hRBBP4<br /> | **[[3gfc]] – hRBBP4<br /> | ||
| - | **[[2xu7]] – hRBBP4 + zinc finger protein ZFPM1 RBBP4-binding domain | + | **[[2xu7]] – hRBBP4 + zinc finger protein ZFPM1 RBBP4-binding domain<br /> |
| + | **[[4pby]], [[4pbz]], [[4pc0]] – hRBBP4 + metastasis-associated protein<br /> | ||
| + | **[[4r7a]] – hRBBP4 + PHD protein 6 peptide<br /> | ||
*Retinoblastoma-binding protein 6 | *Retinoblastoma-binding protein 6 | ||
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**[[3cfs]], [[3cfv]] – hRBBP7 + histone H4 helix | **[[3cfs]], [[3cfv]] – hRBBP7 + histone H4 helix | ||
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| + | *Retinoblastoma-binding protein 8 | ||
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| + | **[[4d2h]] – hRBBP8<br /> | ||
*Retinoblastoma-binding protein 9 | *Retinoblastoma-binding protein 9 | ||
Revision as of 10:25, 27 May 2015
Retinoblastoma-binding protein (RBBP) or histone-binding protein are nuclear proteins implicated in the regulation of transcription and differentiation by the retinoblastoma tumor suppressor protein.
- RBBP1 regulates transcriptional activity.
- RBBP2 demethylates histone H3 at lysine 4.
- RBBP5 is involved in methylation and dimethylation of histone H3.
- RBBP9 blocks the binding of retinoblastoma protein to one of its signaling partners.
3D structures of retinoblastoma-binding protein
Updated on 27-May-2015
