351d

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[[Image:351d.gif|left|200px]]<br /><applet load="351d" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:351d.gif|left|200px]]
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caption="351d, resolution 1.640&Aring;" />
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'''X-RAY CRYSTAL STRUCTURES OF THE HEXAMER DCACGCG: CRYSTALS GROWN IN THE PRESENCE OF RUTHENIUM (II) HEXAMMINE CHLORIDE'''<br />
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{{Structure
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|PDB= 351d |SIZE=350|CAPTION= <scene name='initialview01'>351d</scene>, resolution 1.640&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''X-RAY CRYSTAL STRUCTURES OF THE HEXAMER DCACGCG: CRYSTALS GROWN IN THE PRESENCE OF RUTHENIUM (II) HEXAMMINE CHLORIDE'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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351D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=351D OCA].
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351D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=351D OCA].
==Reference==
==Reference==
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Structure of d(CACGCG).d(CGCGTG) in crystals grown in the presence of ruthenium III hexammine chloride., Karthe P, Gautham N, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):501-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9761846 9761846]
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Structure of d(CACGCG).d(CGCGTG) in crystals grown in the presence of ruthenium III hexammine chloride., Karthe P, Gautham N, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):501-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9761846 9761846]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Gautham, N.]]
[[Category: Gautham, N.]]
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[[Category: z-dna]]
[[Category: z-dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:02:15 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:54:54 2008''

Revision as of 16:54, 20 March 2008


PDB ID 351d

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, resolution 1.640Å
Coordinates: save as pdb, mmCIF, xml



X-RAY CRYSTAL STRUCTURES OF THE HEXAMER DCACGCG: CRYSTALS GROWN IN THE PRESENCE OF RUTHENIUM (II) HEXAMMINE CHLORIDE


Overview

Hexammine ions are strong inducers of the transition from the B-form to the left-handed Z-form in DNA. Here the structure of d(CACGCG). d(CGCGTG) obtained from crystals grown from a drop containing [Ru(NH3)6]Cl3 is reported. The structure is clearly characterized as Z-DNA. When compared with the structure of d(CACGCG).d(CGCGTG)/MgCl2 and that of d(CGCGCG)2, subtle differences are seen, most noticeably in the water structure. Since stable well diffracting crystals grow easily in the presence of [Ru(NH3)6]Cl3 and since this ion is not visible in the electron density it is concluded that the ion plays a non-specific role in stabilizing Z-DNA.

About this Structure

351D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Structure of d(CACGCG).d(CGCGTG) in crystals grown in the presence of ruthenium III hexammine chloride., Karthe P, Gautham N, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):501-9. PMID:9761846

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