367d
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:367d.gif|left|200px]] | + | [[Image:367d.gif|left|200px]] |
| - | + | ||
| - | '''1.2 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/5-BROMO-9-AMINO-DACA COMPLEX''' | + | {{Structure |
| + | |PDB= 367d |SIZE=350|CAPTION= <scene name='initialview01'>367d</scene>, resolution 1.200Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=DA5:5-BROMO-9-AMINO-N-ETHYL(DIAMINOMETHYL)ACRIDINE-4-CARBOXAMIDE'>DA5</scene> and <scene name='pdbligand=BR:BROMIDE ION'>BR</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''1.2 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/5-BROMO-9-AMINO-DACA COMPLEX''' | ||
| + | |||
==About this Structure== | ==About this Structure== | ||
| - | 367D is a [ | + | 367D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=367D OCA]. |
==Reference== | ==Reference== | ||
| - | Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:[http:// | + | Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10052960 10052960] |
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Adams, A.]] | [[Category: Adams, A.]] | ||
| Line 21: | Line 30: | ||
[[Category: modified]] | [[Category: modified]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:55:08 2008'' |
Revision as of 16:55, 20 March 2008
| |||||||
| , resolution 1.200Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | and | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
1.2 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/5-BROMO-9-AMINO-DACA COMPLEX
About this Structure
367D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:10052960
Page seeded by OCA on Thu Mar 20 18:55:08 2008
Categories: Protein complex | Adams, A. | Cardin, C J. | Denny, W A. | Thorpe, J H. | Todd, A K. | BR | DA5 | Complexed with drug | Dna | Double helix | Modified
