4qgn
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Human acireductone dioxygenase with iron ion and L-methionine in active center== |
| - | + | <StructureSection load='4qgn' size='340' side='right' caption='[[4qgn]], [[Resolution|resolution]] 3.05Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4qgn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QGN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acireductone_dioxygenase_(Fe(2+)-requiring) Acireductone dioxygenase (Fe(2+)-requiring)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.54 1.13.11.54] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qgn RCSB], [http://www.ebi.ac.uk/pdbsum/4qgn PDBsum]</span></td></tr> | |
| - | [ | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MTND_HUMAN MTND_HUMAN]] Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.[HAMAP-Rule:MF_03154]<ref>PMID:11602742</ref> <ref>PMID:15938715</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Borowski, T]] | [[Category: Borowski, T]] | ||
| - | [[Category: Niedzialkowska, E]] | ||
| - | [[Category: Milaczewska, A.M]] | ||
[[Category: Chruszcz, M]] | [[Category: Chruszcz, M]] | ||
| + | [[Category: Milaczewska, A M]] | ||
[[Category: Minor, W]] | [[Category: Minor, W]] | ||
| - | [[Category: Petkowski, J | + | [[Category: Niedzialkowska, E]] |
| + | [[Category: Petkowski, J J]] | ||
| + | [[Category: Iron binding]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Rmlc-like cupin]] | ||
Revision as of 15:56, 27 May 2015
Human acireductone dioxygenase with iron ion and L-methionine in active center
| |||||||||||
