3b5n

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:3b5n.gif|left|200px]]<br /><applet load="3b5n" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:3b5n.gif|left|200px]]
-
caption="3b5n, resolution 1.600&Aring;" />
+
 
-
'''Structure of the yeast plasma membrane SNARE complex'''<br />
+
{{Structure
 +
|PDB= 3b5n |SIZE=350|CAPTION= <scene name='initialview01'>3b5n</scene>, resolution 1.600&Aring;
 +
|SITE=
 +
|LIGAND=
 +
|ACTIVITY=
 +
|GENE= SNC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae]), SSO1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae]), SEC9, HSS7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
 +
}}
 +
 
 +
'''Structure of the yeast plasma membrane SNARE complex'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
3B5N is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B5N OCA].
+
3B5N is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B5N OCA].
==Reference==
==Reference==
-
The structure of the yeast plasma membrane SNARE complex reveals destabilizing water-filled cavities., Strop P, Kaiser SE, Vrljic M, Brunger AT, J Biol Chem. 2008 Jan 11;283(2):1113-9. Epub 2007 Oct 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17956869 17956869]
+
The structure of the yeast plasma membrane SNARE complex reveals destabilizing water-filled cavities., Strop P, Kaiser SE, Vrljic M, Brunger AT, J Biol Chem. 2008 Jan 11;283(2):1113-9. Epub 2007 Oct 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17956869 17956869]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
Line 36: Line 45:
[[Category: ubl conjugation]]
[[Category: ubl conjugation]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:03:31 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:56:16 2008''

Revision as of 16:56, 20 March 2008

Image:3b5n.gif


PDB ID 3b5n

Drag the structure with the mouse to rotate
, resolution 1.600Å
Gene: SNC1 (Saccharomyces cerevisiae), SSO1 (Saccharomyces cerevisiae), SEC9, HSS7 (Saccharomyces cerevisiae)
Coordinates: save as pdb, mmCIF, xml



Structure of the yeast plasma membrane SNARE complex


Overview

SNARE proteins form a complex that leads to membrane fusion between vesicles, organelles, and plasma membrane in all eukaryotic cells. We report the 1.7A resolution structure of the SNARE complex that mediates exocytosis at the plasma membrane in the yeast Saccharomyces cerevisiae. Similar to its neuronal and endosomal homologues, the S. cerevisiae SNARE complex forms a parallel four-helix bundle in the center of which is an ionic layer. The S. cerevisiae SNARE complex exhibits increased helix bending near the ionic layer, contains water-filled cavities in the complex core, and exhibits reduced thermal stability relative to mammalian SNARE complexes. Mutagenesis experiments suggest that the water-filled cavities contribute to the lower stability of the S. cerevisiae complex.

About this Structure

3B5N is a Protein complex structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

The structure of the yeast plasma membrane SNARE complex reveals destabilizing water-filled cavities., Strop P, Kaiser SE, Vrljic M, Brunger AT, J Biol Chem. 2008 Jan 11;283(2):1113-9. Epub 2007 Oct 22. PMID:17956869

Page seeded by OCA on Thu Mar 20 18:56:16 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3b5n"
Personal tools