3bbt

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[[Image:3bbt.jpg|left|200px]]<br /><applet load="3bbt" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:3bbt.jpg|left|200px]]
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caption="3bbt, resolution 2.800&Aring;" />
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'''crystal structure of the ErbB4 kinase in complex with lapatinib'''<br />
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{{Structure
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|PDB= 3bbt |SIZE=350|CAPTION= <scene name='initialview01'>3bbt</scene>, resolution 2.800&Aring;
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|SITE= <scene name='pdbsite=AC1:Fmm+Binding+Site+For+Residue+B+91'>AC1</scene> and <scene name='pdbsite=AC2:Fmm+Binding+Site+For+Residue+D+91'>AC2</scene>
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|LIGAND= <scene name='pdbligand=FMM:N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE'>FMM</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1]
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|GENE= ERBB4, HER4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''crystal structure of the ErbB4 kinase in complex with lapatinib'''
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==About this Structure==
==About this Structure==
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3BBT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=FMM:'>FMM</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] Known structural/functional Sites: <scene name='pdbsite=AC1:Fmm+Binding+Site+For+Residue+B+91'>AC1</scene> and <scene name='pdbsite=AC2:Fmm+Binding+Site+For+Residue+D+91'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BBT OCA].
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3BBT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BBT OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: tyrosine-protein kinase]]
[[Category: tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:04:44 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:57:43 2008''

Revision as of 16:57, 20 March 2008


PDB ID 3bbt

Drag the structure with the mouse to rotate
, resolution 2.800Å
Sites: and
Ligands:
Gene: ERBB4, HER4 (Homo sapiens)
Activity: Receptor protein-tyrosine kinase, with EC number 2.7.10.1
Coordinates: save as pdb, mmCIF, xml



crystal structure of the ErbB4 kinase in complex with lapatinib


About this Structure

3BBT is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 18:57:43 2008

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