3bch

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[[Image:3bch.jpg|left|200px]]<br /><applet load="3bch" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:3bch.jpg|left|200px]]
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caption="3bch, resolution 2.15&Aring;" />
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'''Crystal Structure of the Human Laminin Receptor Precursor'''<br />
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{{Structure
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|PDB= 3bch |SIZE=350|CAPTION= <scene name='initialview01'>3bch</scene>, resolution 2.15&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE= RPSA, LAMBR, LAMR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Crystal Structure of the Human Laminin Receptor Precursor'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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3BCH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BCH OCA].
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3BCH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BCH OCA].
==Reference==
==Reference==
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Crystal structure of the human laminin receptor precursor., Jamieson KV, Wu J, Hubbard SR, Meruelo D, J Biol Chem. 2008 Feb 8;283(6):3002-5. Epub 2007 Dec 6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18063583 18063583]
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Crystal structure of the human laminin receptor precursor., Jamieson KV, Wu J, Hubbard SR, Meruelo D, J Biol Chem. 2008 Feb 8;283(6):3002-5. Epub 2007 Dec 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18063583 18063583]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: ribosomal protein]]
[[Category: ribosomal protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:04:49 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:57:52 2008''

Revision as of 16:57, 20 March 2008

Image:3bch.jpg


PDB ID 3bch

Drag the structure with the mouse to rotate
, resolution 2.15Å
Gene: RPSA, LAMBR, LAMR1 (Homo sapiens)
Coordinates: save as pdb, mmCIF, xml



Crystal Structure of the Human Laminin Receptor Precursor


Overview

The human laminin receptor (LamR) interacts with many ligands, including laminin, prions, Sindbis virus, and the polyphenol (-)-epigallocatechin-3-gallate (EGCG), and has been implicated in a number of diseases. LamR is overexpressed on tumor cells, and targeting LamR elicits anti-cancer effects. Here, we report the crystal structure of human LamR, which provides insights into its function and should facilitate the design of novel therapeutics targeting LamR.

About this Structure

3BCH is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of the human laminin receptor precursor., Jamieson KV, Wu J, Hubbard SR, Meruelo D, J Biol Chem. 2008 Feb 8;283(6):3002-5. Epub 2007 Dec 6. PMID:18063583

Page seeded by OCA on Thu Mar 20 18:57:52 2008

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