4d60
From Proteopedia
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| - | ''' | + | ==Structure of a dimeric Plasmodium falciparum profilin mutant== |
| - | + | <StructureSection load='4d60' size='340' side='right' caption='[[4d60]], [[Resolution|resolution]] 3.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4d60]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D60 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D60 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d60 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d60 RCSB], [http://www.ebi.ac.uk/pdbsum/4d60 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[Category: | + | == Function == |
| - | [[Category: Kallio, J | + | [[http://www.uniprot.org/uniprot/PROF_PLAFX PROF_PLAFX]] Essential for the invasive blood stages of the parasite. Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton. Weakly sequesters actin monomers.<ref>PMID:19000816</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bhargav, S P]] | ||
| + | [[Category: Kallio, J P]] | ||
[[Category: Kursula, I]] | [[Category: Kursula, I]] | ||
| - | [[Category: Vahokoski, J]] | ||
[[Category: Kursula, P]] | [[Category: Kursula, P]] | ||
[[Category: Torda, A]] | [[Category: Torda, A]] | ||
| - | [[Category: | + | [[Category: Vahokoski, J]] |
| + | [[Category: Actin binding]] | ||
| + | [[Category: Domain swapping]] | ||
| + | [[Category: Structural protein]] | ||
Revision as of 12:42, 3 June 2015
Structure of a dimeric Plasmodium falciparum profilin mutant
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