4ydi

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'''Unreleased structure'''
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==Crystal structure of broad and potently neutralizing VRC01-class antibody Z258-VRC27.01, isolated from human donor Z258, in complex with HIV-1 gp120 from clade A strain Q23.17==
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<StructureSection load='4ydi' size='340' side='right' caption='[[4ydi]], [[Resolution|resolution]] 3.45&Aring;' scene=''>
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The entry 4ydi is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ydi]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YDI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YDI FirstGlance]. <br>
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Authors: Zhou, T., Srivatsan, S., Kwong, P.D.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ydj|4ydj]], [[4ydk|4ydk]], [[4ydl|4ydl]]</td></tr>
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Description: Crystal structure of broad and potently neutralizing VRC01-class antibody Z258-VRC27.01, isolated from human donor Z258, in complex with HIV-1 gp120 from clade A strain Q23.17
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ydi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ydi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ydi RCSB], [http://www.ebi.ac.uk/pdbsum/4ydi PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Kwong, P.D]]
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== Function ==
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[[http://www.uniprot.org/uniprot/O55774_9HIV1 O55774_9HIV1]] The envelope glyprotein gp160 precursor down-modulates cell surface CD4 antigen by interacting with it in the endoplasmic reticulum and blocking its transport to the cell surface.[RuleBase:RU004292]
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__TOC__
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</StructureSection>
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[[Category: Kwong, P D]]
[[Category: Srivatsan, S]]
[[Category: Srivatsan, S]]
[[Category: Zhou, T]]
[[Category: Zhou, T]]
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[[Category: Antibody]]
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[[Category: Hiv-1]]
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[[Category: Immune system]]

Revision as of 12:47, 3 June 2015

Crystal structure of broad and potently neutralizing VRC01-class antibody Z258-VRC27.01, isolated from human donor Z258, in complex with HIV-1 gp120 from clade A strain Q23.17

4ydi, resolution 3.45Å

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