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4qxz
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of a hypothetical protein from Staphylococcus aureus== |
| + | <StructureSection load='4qxz' size='340' side='right' caption='[[4qxz]], [[Resolution|resolution]] 2.49Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4qxz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QXZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QXZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qxz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qxz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qxz RCSB], [http://www.ebi.ac.uk/pdbsum/4qxz PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The ywpF gene (SAV2097) of the Staphylococcus aureus strain Mu50 encodes the YwpF protein, which may play a role in antibiotic resistance. Here, we report the first crystal structure of the YwpF superfamily from S. aureus at 2.5-A resolution. The YwpF structure consists of two regions: an N-terminal core beta-barrel domain that shows structural similarity to type VI secretion system (T6SS) proteins (e.g., Hcp1, Hcp3, and EvpC) and a C-terminal two-helix pair. Although the monomer structure of S. aureus YwpF resembles those of T6SS proteins, the dimer/tetramer model of S. aureus YwpF is distinct from the functionally important hexameric ring of T6SS proteins. We therefore suggest that the S. aureus YwpF may have a different function compared to T6SS proteins. | ||
| - | + | Crystal structure of YwpF from Staphylococcus aureus reveals its architecture comprised of a beta-barrel core domain resembling type VI secretion system proteins and a two-helix pair.,Lee SJ, Lee KY, Lee KY, Kim DG, Kim SJ, Lee BJ Proteins. 2015 Apr;83(4):781-8. doi: 10.1002/prot.24774. Epub 2015 Feb 28. PMID:25663006<ref>PMID:25663006</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Lee, K | + | __TOC__ |
| - | [[Category: Lee, | + | </StructureSection> |
| - | [[Category: | + | [[Category: Lee, B J]] |
| + | [[Category: Lee, K Y]] | ||
| + | [[Category: Lee, S J]] | ||
| + | [[Category: Beta-barrel]] | ||
| + | [[Category: Unknown function]] | ||
Revision as of 13:59, 10 June 2015
Crystal structure of a hypothetical protein from Staphylococcus aureus
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