4y21

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'''Unreleased structure'''
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==Crystal Structure of Munc13-1 MUN domain==
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<StructureSection load='4y21' size='340' side='right' caption='[[4y21]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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The entry 4y21 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4y21]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y21 FirstGlance]. <br>
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Authors: Yang, X.Y., Wang, S., Sheng, Y., Zhang, M., Zou, W.J., Wu, L.J., Kang, L.J., Rizo, J., Zhang, R.G., Xu, T., Ma, C.
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y21 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4y21 RCSB], [http://www.ebi.ac.uk/pdbsum/4y21 PDBsum]</span></td></tr>
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</table>
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Description:
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== Function ==
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[[Category: Unreleased Structures]]
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[[http://www.uniprot.org/uniprot/UN13A_RAT UN13A_RAT]] Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. Also involved in secretory granule priming in insulin secretion.<ref>PMID:9697857</ref> <ref>PMID:11343654</ref> <ref>PMID:11792326</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Kang, L J]]
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[[Category: Ma, C]]
[[Category: Rizo, J]]
[[Category: Rizo, J]]
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[[Category: Yang, X.Y]]
 
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[[Category: Xu, T]]
 
[[Category: Sheng, Y]]
[[Category: Sheng, Y]]
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[[Category: Wu, L.J]]
 
[[Category: Wang, S]]
[[Category: Wang, S]]
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[[Category: Ma, C]]
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[[Category: Wu, L J]]
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[[Category: Zhang, R.G]]
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[[Category: Xu, T]]
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[[Category: Yang, X Y]]
[[Category: Zhang, M]]
[[Category: Zhang, M]]
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[[Category: Zou, W.J]]
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[[Category: Zhang, R G]]
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[[Category: Kang, L.J]]
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[[Category: Zou, W J]]
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[[Category: Catchr]]
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[[Category: Exocytosis]]
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[[Category: Helical bundle]]

Revision as of 14:10, 10 June 2015

Crystal Structure of Munc13-1 MUN domain

4y21, resolution 2.90Å

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