This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3bpr
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:3bpr.jpg|left|200px]] | + | [[Image:3bpr.jpg|left|200px]] |
| - | + | ||
| - | '''Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor C52''' | + | {{Structure |
| + | |PDB= 3bpr |SIZE=350|CAPTION= <scene name='initialview01'>3bpr</scene>, resolution 2.80Å | ||
| + | |SITE= <scene name='pdbsite=AC1:Na+Binding+Site+For+Residue+B+1'>AC1</scene>, <scene name='pdbsite=AC2:Cl+Binding+Site+For+Residue+C+133'>AC2</scene>, <scene name='pdbsite=AC3:Olp+Binding+Site+For+Residue+A+900'>AC3</scene>, <scene name='pdbsite=AC4:Olp+Binding+Site+For+Residue+B+900'>AC4</scene>, <scene name='pdbsite=AC5:Olp+Binding+Site+For+Residue+C+900'>AC5</scene> and <scene name='pdbsite=AC6:Olp+Binding+Site+For+Residue+D+900'>AC6</scene> | ||
| + | |LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=OLP:2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE'>OLP</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] | ||
| + | |GENE= MERTK, MER ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | }} | ||
| + | |||
| + | '''Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor C52''' | ||
| + | |||
==About this Structure== | ==About this Structure== | ||
| - | 3BPR is a [ | + | 3BPR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPR OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
| Line 36: | Line 45: | ||
[[Category: sgc]] | [[Category: sgc]] | ||
[[Category: signal]] | [[Category: signal]] | ||
| - | [[Category: structural | + | [[Category: structural genomic]] |
[[Category: structural genomics consortium]] | [[Category: structural genomics consortium]] | ||
[[Category: transferase]] | [[Category: transferase]] | ||
| Line 43: | Line 52: | ||
[[Category: vision]] | [[Category: vision]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:00:31 2008'' |
Revision as of 17:00, 20 March 2008
| |||||||
| , resolution 2.80Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | , , , , and | ||||||
| Ligands: | , and | ||||||
| Gene: | MERTK, MER (Homo sapiens) | ||||||
| Activity: | Receptor protein-tyrosine kinase, with EC number 2.7.10.1 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor C52
About this Structure
3BPR is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 19:00:31 2008
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Single protein | Arrowsmith, C H. | Bochkarev, A. | Dhe-Paganon, S. | Edwards, A M. | Huang, X. | Jr, P J.Finerty. | SGC, Structural Genomics Consortium. | Walker, J R. | Weigelt, J. | CL | NA | OLP | Atp-binding | Disease mutation | Glycoprotein | Immunoglobulin domain | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Phosphorylation | Polymorphism | Proto-oncogene | Receptor | Retinitis pigmentosa | Sensory transduction | Sgc | Signal | Structural genomic | Structural genomics consortium | Transferase | Transmembrane | Tyrosine-protein kinase | Vision
