RNA polymerase
From Proteopedia
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**[[2hcn]], [[2hcs]], [[2hfz]] – RNAP polymerase domain – West Nile virus<br /> | **[[2hcn]], [[2hcs]], [[2hfz]] – RNAP polymerase domain – West Nile virus<br /> | ||
**[[2pgg]], [[2pus]] – RNAP – Bursal disease virus<br /> | **[[2pgg]], [[2pus]] – RNAP – Bursal disease virus<br /> | ||
| - | ** | + | **[[2r7o]], [[2r7q]] – SrRNAP – Simian rotavirus<br /> |
**[[4au6]] - RNAP – bovine rotavirus – Cryo-EM<br /> | **[[4au6]] - RNAP – bovine rotavirus – Cryo-EM<br /> | ||
**[[2yi8]], [[2yi9]], [[2yia]], [[2yib]] – IpnvRNAP – Infectious pancreatic necrosis virus<br /> | **[[2yi8]], [[2yi9]], [[2yia]], [[2yib]] – IpnvRNAP – Infectious pancreatic necrosis virus<br /> | ||
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**[[4wsb]] - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2 + RNA<br /> | **[[4wsb]] - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2 + RNA<br /> | ||
| - | |||
*DNA primase | *DNA primase | ||
Revision as of 10:46, 11 June 2015
RNA polymerase (RNAP, DNA primase, dnaG) catalyzes the addition of nucleotides to RNA during transcription. The DNA-dependent eukaryote RNAP are divided to RNAP I (or Pol I) which transcribes ribosomal RNA; RNAP II (or Pol II) transcribes DNA and most snRNA and microRNA; RNAP III (or Pol III) transcribes tRNA and 5S ribosomal RNA.DNA primase (DNAP) is RNAP which catalyzes the synthesis of the RNA primer which complements an ssDNA template and initiates DNA synthesis. dnaG is a bacterial primase. Influenza virus RNA polymerase is composed of 3 subunits. Subunit PA is involved in cap-snatching. Subunit PB1 is involved in RNA synthesis. Subunit PB2 is involved in RNA replication and transcription. It is implicated in endonuclease cleavage of RNA primers. (1qln; blue: nontemplate strand; cyan: template strand; red:RNA). See also Transcription and RNA Processing.
For RNA polymerase from bacteriophage T7 see
- Molecular Playground/T7 RNAP Conformations
- User:Luis E Ramirez-Tapia/T7 RNA polymerase
- Molecular Playground/T7 RNA Polymerase (7 mer int).
For RNA-dependent RNA polymerase from Hepatitis C virus - NS5B - see
- NS5B.
For DNA-dependent RNA polymerase see
For the Thermus thermophilus β' subunit see
For the influenza virus RNA-dependent RNA polymerase PB2 and PA homology model and sequence alignment see
- User:Michael Strong/H1N1/PB2
- User:Michael Strong/H1N1/PB2/MSA
- User:Michael Strong/H1N1/PA
- User:Michael Strong/H1N1/PA/MSA
3D Structures of RNA polymerase
Updated on 11-June-2015
- Created with the participation of Craig T Martin.
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Karsten Theis
