Shikimate dehydrogenase
From Proteopedia
(Difference between revisions)
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**[[3don]] – SeAroE – ''Staphylococcus epidermidis'' <br /> | **[[3don]] – SeAroE – ''Staphylococcus epidermidis'' <br /> | ||
**[[3o8q]] – VcAroE – ''Vibrio cholerae'' <br /> | **[[3o8q]] – VcAroE – ''Vibrio cholerae'' <br /> | ||
| - | **[[3pwz]] – AroE 3 – ''Pseudomonas putida'' <br /> | + | **[[3pwz]], [[4omu]] – AroE 3 – ''Pseudomonas putida'' <br /> |
**[[3phg]] – HpAroE – ''Helicobacter pylori'' <br /> | **[[3phg]] – HpAroE – ''Helicobacter pylori'' <br /> | ||
**[[4foo]], [[4fpx]] – HpAroE (mutant) <br /> | **[[4foo]], [[4fpx]] – HpAroE (mutant) <br /> | ||
**[[3u62]] – AroE – ''Thermotoga maritima'' <br /> | **[[3u62]] – AroE – ''Thermotoga maritima'' <br /> | ||
**[[2nlo]] – CgAroE – ''Corynebacterium glutamicum''<br /> | **[[2nlo]] – CgAroE – ''Corynebacterium glutamicum''<br /> | ||
| + | **[[4p4n]] - MtAroE – ''Mycobacterium tuberculosis''<br /> | ||
| + | **[[4xij]] - AroE – ''Mycobacterium fortuitum''<br /> | ||
*Shikimate dehydrogenase complex with NADP | *Shikimate dehydrogenase complex with NADP | ||
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**[[4fos]], [[4fq8]], [[4fr5]], [[4fsh]] – HpAroE (mutant) + shikimate <br /> | **[[4fos]], [[4fq8]], [[4fr5]], [[4fsh]] – HpAroE (mutant) + shikimate <br /> | ||
**[[3phj]] – HpAroE + 3-dihydroshikimate <br /> | **[[3phj]] – HpAroE + 3-dihydroshikimate <br /> | ||
| + | **[[4p4g]], [[4p4l]] - MtAroE + shikimate <br /> | ||
*Shikimate dehydrogenase complex with NADP and shikimate | *Shikimate dehydrogenase complex with NADP and shikimate | ||
Revision as of 07:20, 16 June 2015
Shikimate dehydrogenase (AroE) catalyzes the conversion of shikimate and NADP+ to 3-dihydroshikimate, NADPH and H+. It is part of the shikimate pathway which is responsible for the biosynthesis of phenylalanine, tyrosine and tryptophan. This pathway is found in bacteria, fungi, plants, algae and parasites and is missing in animals and humans.
3D Structures of shikimate dehydrogenase
Updated on 16-June-2015
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Sohail Jooma
