3bue
From Proteopedia
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| - | [[Image:3bue.jpg|left|200px]] | + | [[Image:3bue.jpg|left|200px]] |
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| - | '''Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis''' | + | {{Structure |
| + | |PDB= 3bue |SIZE=350|CAPTION= <scene name='initialview01'>3bue</scene>, resolution 2.15Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= argR, ahrC, Rv1657, MT1695, MTCY06H11.22 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 Mycobacterium tuberculosis H37Rv]) | ||
| + | }} | ||
| + | |||
| + | '''Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 3BUE is a [ | + | 3BUE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BUE OCA]. |
==Reference== | ==Reference== | ||
| - | Expression, purification and preliminary X-ray analysis of the C-terminal domain of an arginine repressor protein from Mycobacterium tuberculosis., Lu GJ, Garen CR, Cherney MM, Cherney LT, Lee C, James MN, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Nov 1;63(Pt, 11):936-9. Epub 2007 Oct 24. PMID:[http:// | + | Expression, purification and preliminary X-ray analysis of the C-terminal domain of an arginine repressor protein from Mycobacterium tuberculosis., Lu GJ, Garen CR, Cherney MM, Cherney LT, Lee C, James MN, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Nov 1;63(Pt, 11):936-9. Epub 2007 Oct 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18007044 18007044] |
[[Category: Mycobacterium tuberculosis h37rv]] | [[Category: Mycobacterium tuberculosis h37rv]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: oligomerization domain]] | [[Category: oligomerization domain]] | ||
[[Category: repressor]] | [[Category: repressor]] | ||
| - | [[Category: structural | + | [[Category: structural genomic]] |
[[Category: tb structural genomics consortium]] | [[Category: tb structural genomics consortium]] | ||
[[Category: tbsgc]] | [[Category: tbsgc]] | ||
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[[Category: transcription regulation]] | [[Category: transcription regulation]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:01:20 2008'' |
Revision as of 17:01, 20 March 2008
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| , resolution 2.15Å | |||||||
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| Gene: | argR, ahrC, Rv1657, MT1695, MTCY06H11.22 (Mycobacterium tuberculosis H37Rv) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis
Overview
The gene product of an open reading frame Rv1657 from Mycobacterium tuberculosis is a putative arginine repressor protein (ArgR), a transcriptional factor that regulates the expression of arginine-biosynthetic enzymes. Rv1657 was expressed and purified and a C-terminal domain was crystallized using the hanging-drop vapour-diffusion method. Diffraction data were collected and processed to a resolution of 2.15 A. The crystals belong to space group P1 and the Matthews coefficient suggests that the crystals contain six C-terminal domain molecules per unit cell. Previous structural and biochemical studies on the arginine repressor proteins from other organisms have likewise shown the presence of six molecules per unit cell.
About this Structure
3BUE is a Single protein structure of sequence from Mycobacterium tuberculosis h37rv. Full crystallographic information is available from OCA.
Reference
Expression, purification and preliminary X-ray analysis of the C-terminal domain of an arginine repressor protein from Mycobacterium tuberculosis., Lu GJ, Garen CR, Cherney MM, Cherney LT, Lee C, James MN, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Nov 1;63(Pt, 11):936-9. Epub 2007 Oct 24. PMID:18007044
Page seeded by OCA on Thu Mar 20 19:01:20 2008
Categories: Mycobacterium tuberculosis h37rv | Single protein | Cherney, L T. | Cherney, M M. | Garen, C R. | James, M N.G. | Lu, G J. | TBSGC, TB Structural Genomics Consortium. | Amino-acid biosynthesis | Arginine biosynthesis | Cytoplasm | Dna binding protein | Dna-binding | Hexamer | L-arginine binding domain | L-arginine repressor protein | Oligomerization domain | Repressor | Structural genomic | Tb structural genomics consortium | Tbsgc | Transcription | Transcription regulation
