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2mq6
From Proteopedia
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| - | ''' | + | ==Solution structure of Y125F mutant of eRF1 N-domain== |
| - | + | <StructureSection load='2mq6' size='340' side='right' caption='[[2mq6]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2mq6]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MQ6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mq6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mq6 RCSB], [http://www.ebi.ac.uk/pdbsum/2mq6 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | [[ | + | [[http://www.uniprot.org/uniprot/ERF1_HUMAN ERF1_HUMAN]] Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.<ref>PMID:7990965</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Li, Y]] | [[Category: Li, Y]] | ||
| + | [[Category: Pervushin, K]] | ||
[[Category: Pillay, S]] | [[Category: Pillay, S]] | ||
[[Category: Wong, L]] | [[Category: Wong, L]] | ||
| - | [[Category: | + | [[Category: Erf1]] |
| + | [[Category: Rdc]] | ||
| + | [[Category: Translation]] | ||
| + | [[Category: Translation termination]] | ||
Revision as of 15:19, 17 June 2015
Solution structure of Y125F mutant of eRF1 N-domain
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Categories: Li, Y | Pervushin, K | Pillay, S | Wong, L | Erf1 | Rdc | Translation | Translation termination
