4qkz
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==X-ray structure of the catalytic domain of MMP-8 with the inhibitor ML115== |
| - | + | <StructureSection load='4qkz' size='340' side='right' caption='[[4qkz]], [[Resolution|resolution]] 1.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4qkz]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QKZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=QZK:{[(BIPHENYL-4-YLSULFONYL)AMINO]METHANEDIYL}BIS(PHOSPHONIC+ACID)'>QZK</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Neutrophil_collagenase Neutrophil collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.34 3.4.24.34] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qkz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qkz RCSB], [http://www.ebi.ac.uk/pdbsum/4qkz PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/MMP8_HUMAN MMP8_HUMAN]] Can degrade fibrillar type I, II, and III collagens. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Neutrophil collagenase]] | ||
[[Category: Capelli, D]] | [[Category: Capelli, D]] | ||
| - | [[Category: Pochetti, G]] | ||
[[Category: Montanari, R]] | [[Category: Montanari, R]] | ||
| + | [[Category: Pochetti, G]] | ||
| + | [[Category: Tortorella, P]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
Revision as of 15:20, 17 June 2015
X-ray structure of the catalytic domain of MMP-8 with the inhibitor ML115
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