4y05
From Proteopedia
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| - | ''' | + | ==KIF2C short Loop2 construct== |
| - | + | <StructureSection load='4y05' size='340' side='right' caption='[[4y05]], [[Resolution|resolution]] 2.59Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4y05]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y05 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y05 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y05 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4y05 RCSB], [http://www.ebi.ac.uk/pdbsum/4y05 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/KIF2C_HUMAN KIF2C_HUMAN]] In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis.<ref>PMID:19060894</ref> <ref>PMID:21820309</ref> |
| - | [[ | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Gigant, B]] | [[Category: Gigant, B]] | ||
| + | [[Category: Knossow, M]] | ||
| + | [[Category: Wang, W]] | ||
| + | [[Category: Kinesin-13]] | ||
| + | [[Category: Microtubule]] | ||
| + | [[Category: Transport protein]] | ||
| + | [[Category: Tubulin]] | ||
Revision as of 15:23, 17 June 2015
KIF2C short Loop2 construct
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