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Tubulin
From Proteopedia
(Difference between revisions)
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*α-tubulin + β-tubulin | *α-tubulin + β-tubulin | ||
| - | **[[3hkb]], [[3hkc]], [[3hkd]], [[3hke]], [[3n2g]], [[3n2k]], [[3ryc]], [[3ryf]], [[3ryh]], [[3ryi]] – sTUBA+sTUBB+stathmin- | + | **[[3hkb]], [[3hkc]], [[3hkd]], [[3hke]], [[3n2g]], [[3n2k]], [[3ryc]], [[3ryf]], [[3ryh]], [[3ryi]] – sTUBA+sTUBB+stathmin-4 – sheep<br /> |
**[[4f61]] - sTUBA+sTUBB+stathmin-like protein R4<br /> | **[[4f61]] - sTUBA+sTUBB+stathmin-like protein R4<br /> | ||
| - | **[[3ut5]] - sTUBA+sTUBB+stathmin- | + | **[[3ut5]] - sTUBA+sTUBB+stathmin-4 + vinca peptide<br /> |
**[[4eb6]] - sTUBA+sTUBB+stathmin-4<br /> | **[[4eb6]] - sTUBA+sTUBB+stathmin-4<br /> | ||
**[[4drx]] - sTUBA+sTUBB + ankyrin repeat protein<br /> | **[[4drx]] - sTUBA+sTUBB + ankyrin repeat protein<br /> | ||
| + | **[[4lnu]] - sTUBA+sTUBB + ankyrin repeat protein + GDP + GTP + kinesin heavy chain <br /> | ||
| + | **[[4x1i]], [[4x1k]], [[4x1y]], [[4x20]] - sTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + dolastatin + colchicine<br /> | ||
**[[4f6r]] - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein<br /> | **[[4f6r]] - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein<br /> | ||
**[[2wbe]] – bTUBA1D+bTUBB2B+kinesin+AMPPNP – bovine<br /> | **[[2wbe]] – bTUBA1D+bTUBB2B+kinesin+AMPPNP – bovine<br /> | ||
**[[3dco]] - bTUBA+bTUBB+kinesin-like NOD<br /> | **[[3dco]] - bTUBA+bTUBB+kinesin-like NOD<br /> | ||
| - | **[[4ck5]], [[ | + | **[[4ck5]], [[4ck6]], [[4ck7]] - bTUBA+bTUBB+kinesin-like KIF11 motor domain<br /> |
**[[1tvk]] - bTUBA+bTUBB+GDP+GTP+Epothilone A – electron crystallography<br /> | **[[1tvk]] - bTUBA+bTUBB+GDP+GTP+Epothilone A – electron crystallography<br /> | ||
**[[3iz0]] - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy<br /> | **[[3iz0]] - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy<br /> | ||
**[[3edl]] - bTUBA1D+bTUBB2B+kinesin motor domain<br /> | **[[3edl]] - bTUBA1D+bTUBB2B+kinesin motor domain<br /> | ||
**[[2xrp]] - bTUBA1D+bTUBB2B+doublecortin <br /> | **[[2xrp]] - bTUBA1D+bTUBB2B+doublecortin <br /> | ||
| - | **[[3du7]], [[3e22]], [[1z2b]], [[1sa0]], [[1sa1]] – bTUBA1C+bTUBB2B+stathmin- | + | **[[3du7]], [[3e22]], [[1z2b]], [[1sa0]], [[1sa1]], [[1ffx]] – bTUBA1C+bTUBB2B+stathmin-4<br /> |
| - | **[[ | + | **[[4o2a]], [[4iij]], [[4i55]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase<br /> |
| - | + | **[[4wbn]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative<br /> | |
| - | **[[ | + | **[[4o2b]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + colchicine<br /> |
| - | **[[ | + | **[[4tuy]], [[4o4h]], [[4o4i]], [[4o4j]], [[4o4l]], [[4i50]], [[4i4t]], [[4tv8]], [[4tv9]], [[4yj2]], [[4yj3]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + antimitotic agent<br /> |
| - | **[[4o4i]] | + | |
| - | + | ||
| - | + | ||
**[[1jff]] - bTUBA+bTUBB<br /> | **[[1jff]] - bTUBA+bTUBB<br /> | ||
**[[4hna]] - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein<br /> | **[[4hna]] - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein<br /> | ||
| - | **[[ | + | **[[4uxo]], [[4uxp]], [[4uxr]], [[4uxs]], [[4uxy]] - bTUBA+bTUBB + kinesin motor domain + GDP + GTP + taxol – Cryo EM<br /> |
| - | **[[ | + | **[[4uxt]], [[4uy0]] - bTUBA+bTUBB + kinesin heavy chain + GDP + GTP + taxol – Cryo EM<br /> |
| + | **[[4ihj]] - bTUBA+bTUBB+stathmin-4 + tubulin tyrosine ligase + ADP<br /> | ||
**[[3j1t]], [[3j1u]] - bTUBA+bTUBB+ dyenin<br /> | **[[3j1t]], [[3j1u]] - bTUBA+bTUBB+ dyenin<br /> | ||
**[[3j2u]] - bTUBA+bTUBB+kinesin-like KLP10A head domain<br /> | **[[3j2u]] - bTUBA+bTUBB+kinesin-like KLP10A head domain<br /> | ||
| - | **[[4i50]], [[4i4t]] - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase + anti-cancer agent<br /> | ||
**[[2p4n]] - hTUBA+hTUBB+kinesin heavy chain<br /> | **[[2p4n]] - hTUBA+hTUBB+kinesin heavy chain<br /> | ||
**[[2hxf]] - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP – pig<br /> | **[[2hxf]] - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP – pig<br /> | ||
| + | **[[3j6f]] - pTUBA+pTUBB – Cryo EM <br /> | ||
| + | **[[3j6e]] - pTUBA+pTUBB +GMPCPP – Cryo EM <br /> | ||
| + | **[[3j7i]] - pTUBA+pTUBB +GTP – Cryo EM<br /> | ||
| + | **[[3j6g]] - pTUBA+pTUBB +GTP + GDP + taxol – Cryo EM <br /> | ||
| + | **[[3j6h]] - pTUBA+pTUBB +GMPCPP + kinesin heavy chain – Cryo EM <br /> | ||
| + | **[[3j8x]] - pTUBA+pTUBB +GDP + GTP + kinesin heavy chain – Cryo EM <br /> | ||
| + | **[[3j8y]] - pTUBA+pTUBB +GDP + GTP + ATP + kinesin heavy chain – Cryo EM <br /> | ||
| + | **[[3j6p]] - pTUBA+pTUBB +GTP + GDP + taxol + dynein heavy chain – Cryo EM<br /> | ||
**[[2hxh]] - pTUBA+pTUBB+kinesin-like KIF1A+ADP<br /> | **[[2hxh]] - pTUBA+pTUBB+kinesin-like KIF1A+ADP<br /> | ||
**[[1ia0]] - pTUBA+pTUBB+kinesin-like KIF1A+ATP<br /> | **[[1ia0]] - pTUBA+pTUBB+kinesin-like KIF1A+ATP<br /> | ||
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**[[4atx]] - bTUBA1D+bTUBB2B+kinesin motor domain – Cryo EM<br /> | **[[4atx]] - bTUBA1D+bTUBB2B+kinesin motor domain – Cryo EM<br /> | ||
**[[2btq]] – PdTUBA+PdTUBB<br /> | **[[2btq]] – PdTUBA+PdTUBB<br /> | ||
| - | **[[4ffb]] - TUBA+TUBB (mutant) + protein STU2 - yeast | + | **[[4ffb]], [[4u3j]] - TUBA+TUBB (mutant) + protein STU2 - yeast |
*γ-tubulin | *γ-tubulin | ||
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**[[2rhl]] - BsFtsZ+GDP<br /> | **[[2rhl]] - BsFtsZ+GDP<br /> | ||
**[[2rho]] - BsFtsZ+GDP+GTP-gamma-S<br /> | **[[2rho]] - BsFtsZ+GDP+GTP-gamma-S<br /> | ||
| + | **[[4u39]] – BsFtsZ + cell division factor<br /> | ||
**[[2ve9]] - PaFtsZ gamma domain+DNA<br /> | **[[2ve9]] - PaFtsZ gamma domain+DNA<br /> | ||
**[[2vaw]] – PaFtsZ+GDP<br /> | **[[2vaw]] – PaFtsZ+GDP<br /> | ||
Revision as of 06:55, 23 June 2015
Tubulin (TUB) is a constituent of microtubules in eukaryotes. Microtubules are assembled from dimers of α-tubulin (TUBA) and β-tubulin (TUBB) bound to GTP. γ-tubulin (TUBG) is part of the nucleation of microtubules. Human TUB contains several numbered subtypes. FtsZ (Filamenting temperature-sensitive mutant Z) is a prokaryotic homologue of TUB.
3D Structures of Tubulin
Updated on 23-June-2015
