4up1

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'''Unreleased structure'''
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==Crystal structure of native human Thymidylate synthase in active form==
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<StructureSection load='4up1' size='340' side='right' caption='[[4up1]], [[Resolution|resolution]] 2.99&Aring;' scene=''>
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The entry 4up1 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4up1]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UP1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UP1 FirstGlance]. <br>
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Authors: Deschamps, P., Rety, S., Leulliot, N.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4up2|4up2]]</td></tr>
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Description: Crystal structure of native human Thymidylate synthase in active form
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4up1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4up1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4up1 RCSB], [http://www.ebi.ac.uk/pdbsum/4up1 PDBsum]</span></td></tr>
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[[Category: Rety, S]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.<ref>PMID:21876188</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Thymidylate synthase]]
[[Category: Deschamps, P]]
[[Category: Deschamps, P]]
[[Category: Leulliot, N]]
[[Category: Leulliot, N]]
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[[Category: Rety, S]]
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[[Category: Low-salt condition]]
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[[Category: Transferase]]

Revision as of 13:01, 24 June 2015

Crystal structure of native human Thymidylate synthase in active form

4up1, resolution 2.99Å

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