Villin
From Proteopedia
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**[[1yu5]], [[1qqv]] - cVIL headpiece<br /> | **[[1yu5]], [[1qqv]] - cVIL headpiece<br /> | ||
**[[3myc]], [[3mye]], [[3nkj]], [[3mya]], [[3tjw]], [[3trv]], [[3trw]], [[3try]] - cVIL headpiece (mutant)<br /> | **[[3myc]], [[3mye]], [[3nkj]], [[3mya]], [[3tjw]], [[3trv]], [[3trw]], [[3try]] - cVIL headpiece (mutant)<br /> | ||
| - | **[[1vii]], [[2vik]], [[2vil]] - cVIL headpiece - NMR<br /> | + | **[[1vii]], [[2vik]], [[2vil]], [[4cz3]], [[4cz4]] - cVIL headpiece - NMR<br /> |
**[[2ppz]], [[2jm0]] - VIL headpiece (mutant) – synthetic – NMR<br /> | **[[2ppz]], [[2jm0]] - VIL headpiece (mutant) – synthetic – NMR<br /> | ||
**[[2f4k]], [[1wy3]], [[1wy4]], [[1yrf]], [[1yri]] - VIL fragment (mutant) – synthetic<br /> | **[[2f4k]], [[1wy3]], [[1wy4]], [[1yrf]], [[1yri]] - VIL fragment (mutant) – synthetic<br /> | ||
Revision as of 08:12, 25 June 2015
- Villin (VIL) is an actin-binding protein. It contains gelsolin-like domains in its N-terminal and a helical headpiece which binds actin[1].
- Supervillin (SVIL) contains numerous gelsolin-like domains in its C-terminal and interacts with actin.
- Advillin (AVIL) is another actin-binding protein in the gelsolin superfamily which is expressed in the peripheral sensory neurons.
- Cytovillin (CVIL) or ezrin or villin-2 serves as intermediate between plasma membrane and actin cytoskeleton.
3D Structures of Villin
Updated on 25-June-2015
References
- ↑ Friederich E, Vancompernolle K, Louvard D, Vandekerckhove J. Villin function in the organization of the actin cytoskeleton. Correlation of in vivo effects to its biochemical activities in vitro. J Biol Chem. 1999 Sep 17;274(38):26751-60. PMID:10480879
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, David Canner, Jaime Prilusky, Joel L. Sussman
