3kin
From Proteopedia
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| - | [[Image:3kin.gif|left|200px]] | + | [[Image:3kin.gif|left|200px]] |
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| - | '''KINESIN (DIMERIC) FROM RATTUS NORVEGICUS''' | + | {{Structure |
| + | |PDB= 3kin |SIZE=350|CAPTION= <scene name='initialview01'>3kin</scene>, resolution 3.1Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''KINESIN (DIMERIC) FROM RATTUS NORVEGICUS''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 3KIN is a [ | + | 3KIN is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The following page contains interesting information on the relation of 3KIN with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb64_1.html Kinesin]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIN OCA]. |
==Reference== | ==Reference== | ||
| - | The crystal structure of dimeric kinesin and implications for microtubule-dependent motility., Kozielski F, Sack S, Marx A, Thormahlen M, Schonbrunn E, Biou V, Thompson A, Mandelkow EM, Mandelkow E, Cell. 1997 Dec 26;91(7):985-94. PMID:[http:// | + | The crystal structure of dimeric kinesin and implications for microtubule-dependent motility., Kozielski F, Sack S, Marx A, Thormahlen M, Schonbrunn E, Biou V, Thompson A, Mandelkow EM, Mandelkow E, Cell. 1997 Dec 26;91(7):985-94. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9428521 9428521] |
[[Category: Kinesin]] | [[Category: Kinesin]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
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[[Category: motor protein]] | [[Category: motor protein]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:05:31 2008'' |
Revision as of 17:05, 20 March 2008
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| , resolution 3.1Å | |||||||
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| Ligands: | |||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
KINESIN (DIMERIC) FROM RATTUS NORVEGICUS
Overview
The dimeric form of the kinesin motor and neck domain from rat brain with bound ADP has been solved by X-ray crystallography. The two heads of the dimer are connected via a coiled-coil alpha-helical interaction of their necks. They are broadly similar to one another; differences are most apparent in the head-neck junction and in a moderate reorientation of the neck helices in order to adopt to the coiled-coil conformation. The heads show a rotational symmetry (approximately 120 degrees) about an axis close to that of the coiled-coil. This arrangement is unexpected since it is not compatible with the microtubule lattice. In this arrangement, the two heads of a kinesin dimer could not have equivalent interactions with microtubules.
About this Structure
3KIN is a Protein complex structure of sequences from Rattus norvegicus. The following page contains interesting information on the relation of 3KIN with [Kinesin]. Full crystallographic information is available from OCA.
Reference
The crystal structure of dimeric kinesin and implications for microtubule-dependent motility., Kozielski F, Sack S, Marx A, Thormahlen M, Schonbrunn E, Biou V, Thompson A, Mandelkow EM, Mandelkow E, Cell. 1997 Dec 26;91(7):985-94. PMID:9428521
Page seeded by OCA on Thu Mar 20 19:05:31 2008
