4qr9
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of two HMGB1 Box A domains cooperating to underwind and kink a DNA== |
| - | + | <StructureSection load='4qr9' size='340' side='right' caption='[[4qr9]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4qr9]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QR9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QR9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qr9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qr9 RCSB], [http://www.ebi.ac.uk/pdbsum/4qr9 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/HMGB1_RAT HMGB1_RAT]] DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity). |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Acosta-Reyes, F J]] | ||
| + | [[Category: Campos, J L]] | ||
| + | [[Category: Churchill, M E.A]] | ||
| + | [[Category: Malarkey, C S]] | ||
[[Category: Sanchez-Giraldo, R]] | [[Category: Sanchez-Giraldo, R]] | ||
| - | [[Category: Malarkey, C.S]] | ||
[[Category: Saperas, N]] | [[Category: Saperas, N]] | ||
| - | [[Category: | + | [[Category: Architectural factor]] |
| - | [[Category: | + | [[Category: Bend dna]] |
| + | [[Category: Box a domain]] | ||
| + | [[Category: Chromatin]] | ||
| + | [[Category: Dna binding protein]] | ||
| + | [[Category: Dna-binding]] | ||
| + | [[Category: High mobility group]] | ||
| + | [[Category: Hmg-box]] | ||
| + | [[Category: Hmgb1]] | ||
| + | [[Category: Kink dna]] | ||
| + | [[Category: Minor groove]] | ||
| + | [[Category: Nucleus]] | ||
Revision as of 12:18, 1 July 2015
Crystal structure of two HMGB1 Box A domains cooperating to underwind and kink a DNA
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