4wmy
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Structure of Human intelectin-1 in complex with allyl-beta-galactofuranose== |
| - | + | <StructureSection load='4wmy' size='340' side='right' caption='[[4wmy]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4wmy]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WMY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WMY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3S6:PROP-2-EN-1-YL+BETA-D-GALACTOFURANOSIDE'>3S6</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wmq|4wmq]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wmy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wmy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wmy RCSB], [http://www.ebi.ac.uk/pdbsum/4wmy PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ITLN1_HUMAN ITLN1_HUMAN]] Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.<ref>PMID:11313366</ref> <ref>PMID:16531507</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Forest, K T]] | ||
| + | [[Category: Kiessling, L L]] | ||
[[Category: Wangkanont, K]] | [[Category: Wangkanont, K]] | ||
| - | [[Category: | + | [[Category: Calcium]] |
| - | [[Category: | + | [[Category: Carbohydrate-binding]] |
| + | [[Category: Diol]] | ||
| + | [[Category: Disulfide-linked]] | ||
| + | [[Category: Galactofuranose]] | ||
| + | [[Category: Galactose]] | ||
| + | [[Category: Innate immunity]] | ||
| + | [[Category: Lectin]] | ||
| + | [[Category: Microbe-binding]] | ||
| + | [[Category: Microbe-specific]] | ||
| + | [[Category: Sugar binding protein]] | ||
Revision as of 12:21, 1 July 2015
Structure of Human intelectin-1 in complex with allyl-beta-galactofuranose
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