This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4wmy
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Structure of Human intelectin-1 in complex with allyl-beta-galactofuranose== |
| - | + | <StructureSection load='4wmy' size='340' side='right' caption='[[4wmy]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4wmy]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WMY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WMY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3S6:PROP-2-EN-1-YL+BETA-D-GALACTOFURANOSIDE'>3S6</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wmq|4wmq]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wmy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wmy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wmy RCSB], [http://www.ebi.ac.uk/pdbsum/4wmy PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ITLN1_HUMAN ITLN1_HUMAN]] Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.<ref>PMID:11313366</ref> <ref>PMID:16531507</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Forest, K T]] | ||
| + | [[Category: Kiessling, L L]] | ||
[[Category: Wangkanont, K]] | [[Category: Wangkanont, K]] | ||
| - | [[Category: | + | [[Category: Calcium]] |
| - | [[Category: | + | [[Category: Carbohydrate-binding]] |
| + | [[Category: Diol]] | ||
| + | [[Category: Disulfide-linked]] | ||
| + | [[Category: Galactofuranose]] | ||
| + | [[Category: Galactose]] | ||
| + | [[Category: Innate immunity]] | ||
| + | [[Category: Lectin]] | ||
| + | [[Category: Microbe-binding]] | ||
| + | [[Category: Microbe-specific]] | ||
| + | [[Category: Sugar binding protein]] | ||
Revision as of 12:21, 1 July 2015
Structure of Human intelectin-1 in complex with allyl-beta-galactofuranose
| |||||||||||
