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4xa4
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal Structure of the coiled-coil surrounding Skip 3 of MYH7== |
| - | + | <StructureSection load='4xa4' size='340' side='right' caption='[[4xa4]], [[Resolution|resolution]] 2.33Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4xa4]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XA4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XA4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xa1|4xa1]], [[4xa3|4xa3]], [[4xa6|4xa6]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xa4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xa4 RCSB], [http://www.ebi.ac.uk/pdbsum/4xa4 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/XRCC4_HUMAN XRCC4_HUMAN]] Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.<ref>PMID:8548796</ref> <ref>PMID:10854421</ref> <ref>PMID:10757784</ref> <ref>PMID:16412978</ref> |
| - | [[ | + | == References == |
| - | [[ | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Buvoli, A]] | [[Category: Buvoli, A]] | ||
| - | [[Category: Taylor, K.C]] | ||
[[Category: Buvoli, M]] | [[Category: Buvoli, M]] | ||
| - | [[Category: Korkmaz, E | + | [[Category: Heinz, N T]] |
| - | [[Category: | + | [[Category: Korkmaz, E N]] |
| + | [[Category: Leinwand, L A]] | ||
[[Category: Qiang, C]] | [[Category: Qiang, C]] | ||
| + | [[Category: Rayment, I]] | ||
| + | [[Category: Taylor, K C]] | ||
| + | [[Category: Zheng, Y]] | ||
| + | [[Category: Cardiac]] | ||
| + | [[Category: Coiled coil]] | ||
| + | [[Category: Eb1]] | ||
| + | [[Category: Fusion]] | ||
| + | [[Category: Gp7]] | ||
| + | [[Category: Motor protein]] | ||
| + | [[Category: Myh7]] | ||
| + | [[Category: Myosin]] | ||
| + | [[Category: Skip residue]] | ||
Revision as of 12:22, 1 July 2015
Crystal Structure of the coiled-coil surrounding Skip 3 of MYH7
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Categories: Buvoli, A | Buvoli, M | Heinz, N T | Korkmaz, E N | Leinwand, L A | Qiang, C | Rayment, I | Taylor, K C | Zheng, Y | Cardiac | Coiled coil | Eb1 | Fusion | Gp7 | Motor protein | Myh7 | Myosin | Skip residue
