Hepatocyte growth factor activator

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(New page: <StructureSection load='2r0k' size='340' side='right' caption='Human hepatocyte growth factor activator complex with antibody light chain (PDB code 2r0k)' scene=''> '''Hepatocyte grow...)
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<StructureSection load='2r0k' size='340' side='right' caption='Human hepatocyte growth factor activator (grey) complex with antibody light (red) and heavy (aqua) chains (PDB code [[2r0k]])' scene=''>
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<StructureSection load='2r0k' size='340' side='right' caption='Human hepatocyte growth factor activator complex with antibody light chain (PDB code [[2r0k]])' scene=''>
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'''Hepatocyte growth factor activator''' (HGFA) is a serine protease which links tissue injury to activation of hepatocyte growth factor (HGF). HGFA converts HGF from its latent single-chain form to a heterodimeric active form. HGFA is synthesized as an inactive precursor which is converted to a heterodimer via proteolysis as a result of tissue injury.
'''Hepatocyte growth factor activator''' (HGFA) is a serine protease which links tissue injury to activation of hepatocyte growth factor (HGF). HGFA converts HGF from its latent single-chain form to a heterodimeric active form. HGFA is synthesized as an inactive precursor which is converted to a heterodimer via proteolysis as a result of tissue injury.
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[[1ybw]] – hHGFA protease domain – human<BR />
[[1ybw]] – hHGFA protease domain – human<BR />
[[1yc0]] – hHGFA protease domain + Kunitz-type protease inhibitor<BR />
[[1yc0]] – hHGFA protease domain + Kunitz-type protease inhibitor<BR />
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[[2r0k]] – hHGFA protease domain + antibody light chain<BR />
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[[2r0l]], [[2r0k]], [[2wub]], [[2wuc]], [[3k2u]] – hHGFA protease domain + antibody <BR />
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[[2r0l]], [[2wub]], [[2wuc]], [[3k2u]] – hHGFA protease domain + antibody <BR />
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== References ==
== References ==
<references/>
<references/>

Revision as of 09:46, 2 July 2015

Human hepatocyte growth factor activator (grey) complex with antibody light (red) and heavy (aqua) chains (PDB code 2r0k)

Drag the structure with the mouse to rotate

3D Structures of hepatocyte growth factor activator

Updated on 02-July-2015

1ybw – hHGFA protease domain – human
1yc0 – hHGFA protease domain + Kunitz-type protease inhibitor
2r0l, 2r0k, 2wub, 2wuc, 3k2u – hHGFA protease domain + antibody

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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