Arrestin

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(New page: <StructureSection load='2wtr' size='340' side='right' caption='Bovine arrestin-2 (PDB code 2wtr)' scene=''> '''Arrestin''' (ARR) is a ubiquitous protein which binds to the G protein-c...)
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'''Arrestin''' (ARR) is a ubiquitous protein which binds to the G protein-coupled receptor after its phosphorylation. ARR binding blocks further G protein-mediated signaling and redirects signaling to alternative non-G protein-independent pathways. Hence, ARR are versatile adaptor molecules which can also activate signaling cascades and are involved in nuclear functions.
'''Arrestin''' (ARR) is a ubiquitous protein which binds to the G protein-coupled receptor after its phosphorylation. ARR binding blocks further G protein-mediated signaling and redirects signaling to alternative non-G protein-independent pathways. Hence, ARR are versatile adaptor molecules which can also activate signaling cascades and are involved in nuclear functions.

Revision as of 08:25, 7 July 2015

Bovine arrestin-2 complex with Ba+2 ions (PDB code 2wtr)

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3D Structures of arrestin

Updated on 07-July-2015

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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