Symplekin
From Proteopedia
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| - | + | <StructureSection load='3o2s' size='340' side='right' caption='Human symplekin N terminal (grey) complex with RNA polymerase II subunit A C terminal phosphatase (green) and phosphate ion (PDB code [[3o2s]])' scene=''> | |
| - | <StructureSection load='3o2s' size='340' side='right' caption='Human symplekin N terminal complex with RNA polymerase II subunit A C terminal phosphatase (PDB code [[3o2s]])' scene=''> | + | |
'''Symplekin''' (SMPK) is a scaffold protein recruiting regulatory factors to the multimolecular complex involved in histone mRNA 3’-end processing. SMPK is involved in pre-mRNA polyadenylation. It enhances the activity of RNA polymerase II subunit A C terminal phosphatase (Ssu72). | '''Symplekin''' (SMPK) is a scaffold protein recruiting regulatory factors to the multimolecular complex involved in histone mRNA 3’-end processing. SMPK is involved in pre-mRNA polyadenylation. It enhances the activity of RNA polymerase II subunit A C terminal phosphatase (Ssu72). | ||
Revision as of 09:53, 8 July 2015
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3D Structures of symplekin
Updated on 08-July-2015
3gs3 – DmSMPK N terminal – Drosophila melanogaster
3o2t, 3odr – hSMPK N terminal – human
3ods – hSMPK N terminal (mutant)
3o2s – hSMPK N terminal + RNA polymerase II subunit A C terminal phosphatase
4h3h, 3o2q, 4h3k – hSMPK N terminal + RNA polymerase II subunit A C terminal phosphatase + phosphorylated peptide
4imi, 4imj – DmSMPK N terminal + RNA polymerase II subunit A C terminal phosphatase + phosphorylated peptide
