4wkf
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (2.5mM) at 1.10 A resolution== |
| - | + | <StructureSection load='4wkf' size='340' side='right' caption='[[4wkf]], [[Resolution|resolution]] 1.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4wkf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WKF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBS:DI(N-ACETYL-D-GLUCOSAMINE)'>CBS</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wkf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wkf RCSB], [http://www.ebi.ac.uk/pdbsum/4wkf PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[ | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/CHIT1_HUMAN CHIT1_HUMAN]] Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.<ref>PMID:7592832</ref> <ref>PMID:7836450</ref> <ref>PMID:9748235</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chitinase]] | ||
[[Category: Cachau, R]] | [[Category: Cachau, R]] | ||
| - | [[Category: Mitschler, A]] | ||
| - | [[Category: Harlos, K]] | ||
| - | [[Category: Zhao, Y]] | ||
[[Category: Cousido-Siah, A]] | [[Category: Cousido-Siah, A]] | ||
| + | [[Category: Fadel, F]] | ||
| + | [[Category: Harlos, K]] | ||
[[Category: Howard, E]] | [[Category: Howard, E]] | ||
| - | [[Category: Ruiz, F | + | [[Category: Mitschler, A]] |
| + | [[Category: Podjarny, A]] | ||
| + | [[Category: Ruiz, F X]] | ||
| + | [[Category: Zhao, Y]] | ||
| + | [[Category: Catalytic mechanism]] | ||
| + | [[Category: Chit1]] | ||
| + | [[Category: Gh18 chitinase]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Hydrolysis]] | ||
| + | [[Category: Protonation state]] | ||
Revision as of 14:52, 8 July 2015
Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (2.5mM) at 1.10 A resolution
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Categories: Chitinase | Cachau, R | Cousido-Siah, A | Fadel, F | Harlos, K | Howard, E | Mitschler, A | Podjarny, A | Ruiz, F X | Zhao, Y | Catalytic mechanism | Chit1 | Gh18 chitinase | Hydrolase | Hydrolysis | Protonation state
