Kelch-like protein

(Difference between revisions)

Revision as of 10:27, 9 July 2015

Human Kelch-like protein19 (Keap1) Kelch domain (dark green) complex with NRF2 Neh2 peptide (light green) (PDB code 4ifl)

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Updated on 09-July-2015

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 <StructureSection load='4ifl' size='340' side='right' caption='Human Kelch-like protein19 (Keap1) Kelch domain (dark green) complex with NRF2 Neh2 peptide (light green) (PDB code [[4ifl]])' scene=''>
-'''Kelch-like proteins''' (KLHL) contain multiple Kelch motifs.  This motif is about 50 residues long and forms a four-stranded beta-sheet blade.  Six to Eight such blades form a circular b-propeller domain.  B-prepellers are involved in protein-protein interactions.  The N-terminal of KLHL contains other protein domains like BTB (Broad-Tramtrack-Bric-a-brac) which is also involved in protein-protein interactions.
+'''Kelch-like proteins''' (KLHL) contain multiple Kelch motifs.  This motif is about 50 residues long and forms a four-stranded β-sheet blade.  Six to Eight such blades form a circular β-propeller domain.  β-prepellers are involved in protein-protein interactions.  The N-terminal of KLHL contains other protein domains like BTB (Broad-Tramtrack-Bric-a-brac) which is also involved in protein-protein interactions.
 == Function ==