Wiskott-Aldrich syndrome protein
From Proteopedia
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'''Wiskott-Aldrich syndrome protein''' (WASP) is involved in nucleating of new F-actin. In the autoinhibited form of WASP a region of the N-terminal interacts with a region of its C-terminal. This interaction is disrupted by CDC42 and phosphatidylinositol 4,5-bisphosphate (PIP2) resulting in the active WASP. '''N-WASP''' (Neural WASP) belongs to the WASP family of proteins. Human N-WASP stimulates the actin-nucleating activity. N-WASP induces actin polymerization in the Shigella bacterium. This bacterium causes dysentery. | '''Wiskott-Aldrich syndrome protein''' (WASP) is involved in nucleating of new F-actin. In the autoinhibited form of WASP a region of the N-terminal interacts with a region of its C-terminal. This interaction is disrupted by CDC42 and phosphatidylinositol 4,5-bisphosphate (PIP2) resulting in the active WASP. '''N-WASP''' (Neural WASP) belongs to the WASP family of proteins. Human N-WASP stimulates the actin-nucleating activity. N-WASP induces actin polymerization in the Shigella bacterium. This bacterium causes dysentery. | ||
Revision as of 10:04, 15 July 2015
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3D Structures of Wiskott-Aldrich syndrome protein
Updated on 15-July-2015
