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5bo9
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Structure of human sialyltransferase ST8SiaIII in complex with CMP-3FNeu5Ac and Sia-6S-LacNAc== |
| - | + | <StructureSection load='5bo9' size='340' side='right' caption='[[5bo9]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5bo9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BO9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSF:CYTIDINE-5-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC+ACID'>CSF</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NGS:2-(ACETYLAMINO)-2-DEOXY-6-O-SULFO-BETA-D-GLUCOPYRANOSE'>NGS</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5bo8|5bo8]], [[5bo6|5bo6]], [[5bo7|5bo7]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bo9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5bo9 RCSB], [http://www.ebi.ac.uk/pdbsum/5bo9 PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/SIA8C_HUMAN SIA8C_HUMAN]] May transfer sialic acid through alpha-2,8-linkages to alpha-2,3-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid.<ref>PMID:10766765</ref> <ref>PMID:9826427</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Strynadka, N C.J]] | ||
[[Category: Volkers, G]] | [[Category: Volkers, G]] | ||
| - | [[Category: | + | [[Category: Worrall, L]] |
| + | [[Category: Acceptor]] | ||
| + | [[Category: Donor]] | ||
| + | [[Category: Sialyltransferase]] | ||
| + | [[Category: Ternary complex]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 13:40, 15 July 2015
Structure of human sialyltransferase ST8SiaIII in complex with CMP-3FNeu5Ac and Sia-6S-LacNAc
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