5bo9

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'''Unreleased structure'''
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==Structure of human sialyltransferase ST8SiaIII in complex with CMP-3FNeu5Ac and Sia-6S-LacNAc==
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<StructureSection load='5bo9' size='340' side='right' caption='[[5bo9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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The entry 5bo9 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5bo9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BO9 FirstGlance]. <br>
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Authors: Volkers, G., Worrall, L., Strynadka, N.C.J.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSF:CYTIDINE-5-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC+ACID'>CSF</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NGS:2-(ACETYLAMINO)-2-DEOXY-6-O-SULFO-BETA-D-GLUCOPYRANOSE'>NGS</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5bo8|5bo8]], [[5bo6|5bo6]], [[5bo7|5bo7]]</td></tr>
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Description: Structure of a Glycosyltransferase in Complex with Donor/Acceptor
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bo9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5bo9 RCSB], [http://www.ebi.ac.uk/pdbsum/5bo9 PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Worrall, L]]
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== Function ==
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[[http://www.uniprot.org/uniprot/SIA8C_HUMAN SIA8C_HUMAN]] May transfer sialic acid through alpha-2,8-linkages to alpha-2,3-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid.<ref>PMID:10766765</ref> <ref>PMID:9826427</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Strynadka, N C.J]]
[[Category: Volkers, G]]
[[Category: Volkers, G]]
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[[Category: Strynadka, N.C.J]]
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[[Category: Worrall, L]]
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[[Category: Acceptor]]
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[[Category: Donor]]
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[[Category: Sialyltransferase]]
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[[Category: Ternary complex]]
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[[Category: Transferase]]

Revision as of 13:40, 15 July 2015

Structure of human sialyltransferase ST8SiaIII in complex with CMP-3FNeu5Ac and Sia-6S-LacNAc

5bo9, resolution 2.30Å

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