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5c5c
From Proteopedia
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| - | ''' | + | ==Human metabotropic glutamate receptor 7, extracellular ligand binding domain== |
| - | + | <StructureSection load='5c5c' size='340' side='right' caption='[[5c5c]], [[Resolution|resolution]] 1.86Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5c5c]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C5C FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c5c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5c5c RCSB], [http://www.ebi.ac.uk/pdbsum/5c5c PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/GRM7_HUMAN GRM7_HUMAN]] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.<ref>PMID:9473604</ref> |
| - | [[ | + | == References == |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
| + | [[Category: Dobrovetsky, E]] | ||
| + | [[Category: Dong, A]] | ||
| + | [[Category: Edwards, A M]] | ||
| + | [[Category: Hutchinson, A]] | ||
| + | [[Category: Structural genomic]] | ||
[[Category: Tempel, W]] | [[Category: Tempel, W]] | ||
| - | [[Category: | + | [[Category: Glutamate receptor]] |
| - | [[Category: | + | [[Category: Glutamic acid binding]] |
| - | [[Category: | + | [[Category: Mglur7]] |
| + | [[Category: Sgc]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 13:40, 15 July 2015
Human metabotropic glutamate receptor 7, extracellular ligand binding domain
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