5c5c

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "5c5c" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
+
==Human metabotropic glutamate receptor 7, extracellular ligand binding domain==
-
 
+
<StructureSection load='5c5c' size='340' side='right' caption='[[5c5c]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
-
The entry 5c5c is ON HOLD
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[5c5c]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C5C FirstGlance]. <br>
-
Authors: Dong, A., Dobrovetsky, E., Hutchinson, A., Tempel, W., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Structural Genomics Consortium (SGC)
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c5c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5c5c RCSB], [http://www.ebi.ac.uk/pdbsum/5c5c PDBsum]</span></td></tr>
-
Description: Human metabotropic glutamate receptor 7, extracellular ligand binding domain
+
</table>
-
[[Category: Unreleased Structures]]
+
== Function ==
-
[[Category: Hutchinson, A]]
+
[[http://www.uniprot.org/uniprot/GRM7_HUMAN GRM7_HUMAN]] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.<ref>PMID:9473604</ref>
-
[[Category: Dong, A]]
+
== References ==
-
[[Category: Dobrovetsky, E]]
+
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Bountra, C]]
 +
[[Category: Dobrovetsky, E]]
 +
[[Category: Dong, A]]
 +
[[Category: Edwards, A M]]
 +
[[Category: Hutchinson, A]]
 +
[[Category: Structural genomic]]
[[Category: Tempel, W]]
[[Category: Tempel, W]]
-
[[Category: Arrowsmith, C.H]]
+
[[Category: Glutamate receptor]]
-
[[Category: Edwards, A.M]]
+
[[Category: Glutamic acid binding]]
-
[[Category: Structural Genomics Consortium (Sgc)]]
+
[[Category: Mglur7]]
 +
[[Category: Sgc]]
 +
[[Category: Signaling protein]]

Revision as of 13:40, 15 July 2015

Human metabotropic glutamate receptor 7, extracellular ligand binding domain

5c5c, resolution 1.86Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools